Results 121 to 130 of about 10,481,084 (312)

A consensus guide to preclinical indirect calorimetry experiments.

Understanding the complex factors influencing mammalian metabolism and body weight homeostasis is a long-standing challenge requiring knowledge of energy intake, absorption and expenditure.
Tiganis, Tony, James, David E, Heymsfield, Steven B., Thyfault, John P, Auwerx, Johan, Hevener, Andrea L., Allison, David B., Austad, Steven N, Wolfrum, Christian, Gerhart-Hines, Zachary, Xu, Ying, de Cabo, Rafael, Medina‐Gómez, Gema, Selloum, Mohammed, Scherer, Philipp E, Grobe, Justin L, Speakman, John R, Spiegelman, Bruce M., Habegger, Kirk M., Ayala, Julio E, Reitman, Marc L, Titchenell, Paul M., Škop, Vojtěch, Ferrante, Anthony W., Speakman, John R., Shulman, Gerald I., Baur, Joseph A, Lo, James C., MacLean, Paul S, Steinberg, Gregory R., Hartig, Sean M, Rensen, Patrick C N, Churchill, Gary A., Banks, Alexander S, de Angelis, Martin Hrabě, Williams, Ashley S., Gupta, Rana K., Ansarullah,, Lodhi, Irfan J., Klingenspor, Martin, Chen, Shuai, Kooijman, Sander, Mirmira, Raghavendra G, Grobe, Justin L., Williams, Ashley S, Carobbio, Stefania, Finck, Brian N., Steinberg, Gregory R, Donato, Jose, Rutkowsky, Jennifer M, Ward, Christopher S, Sedlacek, Radislav, Elias, Carol F, Rensen, Patrick C.N., Soukas, Alexander A, Ward, Christopher, Velloso, Licio A, Allison, David B, Morrison, Christopher D, Müller, Timo D., Elias, Carol F., MacLean, Paul S., Müller, Timo D, Dall, Morten, Potthoff, Matthew J, Vidal-Puig, Antonio, Ferrante, Anthony W, Banks, Alexander S., Rozman, Jan, Morton, Gregory J., Ogawa, Yoshihiro, Reguera, David Pajuelo, Holman, Corey D., Kazak, Lawrence, McGuinness, Owen P, Reitman, Marc L., Hevener, Andrea L, Hartig, Sean M., Velloso, Lı́cio A., Thyfault, John P., Austad, Steven N., Ayala, Julio E., Vidal‐Puig, Antonio, Zierath, Juleen R, Svensson, Katrin J., Mirmira, Raghavendra G., Alquier, Thierry, The International Indirect Calorimetry Consensus Committee (IICCC, Galgani, José E., Churchill, Gary, Potthoff, Matthew J., Morton, Gregory J, Shulman, Gerald I, Spiegelman, Bruce M, Morrison, Christopher D., Lodhi, Irfan J, Sakamoto, Kei, Scherer, Philipp E., Gupta, Rana K, Qi, Nathan, Turner, Nigel, Zierath, Juleen R., Dragano, Nathalia Romanelli Vicente, McGuinness, Owen P., Schwartz, Gary J., Goodyear, Laurie J., Kong, Xingxing, Kim, Jae Bum, Holman, Corey D, Rutkowsky, Jennifer M., Shaikh, Saame Raza, Svensson, Katrin J, Xu, Allison, Medina-Gómez, Gema, Gerhart‐Hines, Zachary, Goodyear, Laurie J, Habegger, Kirk M, Galgani, Jose E, Pajuelo-Reguera, David, Lantier, Louise, Finck, Brian N, James, David E., Baur, Joseph A., Dragano, Nathalia R V, Schwartz, Gary J, Heymsfield, Steven B, Lo, James C, Lloyd, K C Kent, Soukas, Alexander A., Xu, Allison W, Lloyd, K. C. Kent, Titchenell, Paul M   +131 more
core   +1 more source

Indirect effects of violence [PDF]

Nature Human Behaviour, 2019
openaire   +2 more sources

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Indirect inference in spatial autoregression

, 2014
Ordinary least squares (OLS) is well-known to produce an inconsistent estimator of the spatial parameter in pure spatial autoregression (SAR). This paper explores the potential of indirect inference to correct the inconsistency of OLS.
Rossi, Francesca, Phillips, Peter C.B., Kyriacou, Maria   +2 more
core   +1 more source

Indirect Roles of Immunophenotypes in the Association Between Glycerophospholipid Metabolism and Endometrial Cancer Risk: A Mendelian Randomization Study

International Journal of Women's Health
Yichen Shen,1,* Yijing Yan,2,* Peizhe Lin,3,* Yulin Wang,1 Yafang Li,1 Huhu Li,4 Yanqi Li,1 Yongna Dai1 1School of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, People’s Republic of ...
Shen Y, Yan Y, Lin P, Wang Y, Li Y, Li H, Li Y, Dai Y   +7 more
doaj  

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Generalised Translation of Indirect Utility Functions [PDF]

This paper considers the derivation of new demand systems from existing ones through replacing an indirect utility function ) , ( y U p by } ) / ( , { j y p y y U j j â ã Ó . p , where p is a vector of prices and y is income.
Denis Conniffe
core  

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Measuring Indirect Reciprocity: Whose Back Do We Scratch? [PDF]

This paper presents an experimental investigation of strong indirect reciprocity. We examine both generalized indirect reciprocity (if A helps B then B helps C) and social indirect reciprocity (if A helps B then C helps A), in a setting where reciprocal ...
Luca Stanca
core