Results 61 to 70 of about 1,223,886 (257)
Advanced Science, EarlyView.Our research unveiled a regulatory paradigm wherein TRIM25 orchestrates the ubiquitin‐mediated degradation of UGDH. UGDH modulates the protein stability of TJP1 by regulating O‐GlcNAcylation levels, effectively impeding the metastasis of ccRCC. Our insights elevate UGDH to a pivotal biomarker and tumor suppressor, marking the first demonstration that ...
Xiaolin Chen +13 more
wiley +1 more source
Advanced Science, EarlyView.. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li +15 more
wiley +1 more source
Food and Agricultural Immunology, 2018 A polyclonal antibody-based indirect ELISA for the sensitive and specific detection of osmotolerant Zygosaccharomyces rouxii was established. The reactivity of the polyclonal antibodies (pAbs) with Z. rouxii was confirmed by immunofluorescence. The ELISA
Hong Guo +5 more
doaj +1 more source
Advanced Science, EarlyView.We demonstrate a novel therapy for traumatic brain injury TBI using a LIPUS‐responsive Piezoelectric fibrous membrane. It targets microglial mitochondria via in situ electrical signals, restoring homeostasis and reducing oxidative stress to promote an anti‐inflammatory M2 phenotype.
Wei Li +9 more
wiley +1 more source
Veterinary Medicine: Research and Reports, 2022 Jirata Shiferaw,1 Firaol Shifara,2 Misgana Tefera,1 Abdi Feyisa,3 Yobsan Tamiru4 1Department of Pathology and Parasitology, Addis Ababa University College of Veterinary Medicine and Agriculture, Bishoftu, Ethiopia; 2College of Natural and Computational ...
Shiferaw J +4 more
doaj
Indirect ELISA for rapid diagnosis of Equine Influenza
, 2020 Se desarrolló un ELISA indirecto para el dia~nóstico de Influenza Equina y se estudió comparativamente con la inhibición de la hemoagluti:-ación. Se elaboró un antígeno a partir de líquido alantoideo infectado sobre el que se realizó una precipitación ...
Vila Roza, María Verónica +6 more
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Episode 77: Empathy and Animal Ethics with Elisa Aaltola
, 2018 In this episode of Knowing Animals we speak to Elisa Aaltola from the University of East Finland. We discuss her latest book ‘Varieties of Empathy: Moral Psychology and Animal Ethics’ which is published by Rowman ...
O'Sullivan, Siobhan, Aaltola, Elisa
core +1 more source
Advanced Science, EarlyView.Local stress concentration disrupts metabolic homeostasis and induces inflammation in the nucleus pulposus (NP), thereby accelerating intervertebral disc degeneration (IDD). A biomimetic HA/ChS hydrogel millimeter sphere (ChS@HM) is developed to enable synergistic stress dispersion and sustained hydration lubrication.
Ang Li +4 more
wiley +1 more source
Comparative Assay on Anti-dengue IgM Antibodies by the Indirect ELISA and IgM-capture ELISA [PDF]
, 1993 Anti-dengue IgM antibodies were measured by the indirect ELISA and IgM-capture ELISA using type 2 and 3 dengue antigens on dengue patients' sera. The assay results depended more strongly on the assay method than the serotype of dengue antigen used in the
Kheong, Chew Tong +3 more
core +3 more sources
Establishment of an indirect ELISA method for detection of human cytomegalovirus [PDF]
精准医学杂志Objective To establish an indirect ELISA method for the detection of human cytomegalovirus (HCMV) based on HCMV IE1/pp65/pp150 recombinant protein. Methods From June to December 2024, 5 serum samples from HCMV IgG-positive patients, 50 serum samples from
LI Xu, WANG Shan, HUANG Huan, WANG Bin, QIAN Dongmeng
doaj +1 more source