Results 71 to 80 of about 57,228 (363)

Achieving the Dispatchability of Distribution Feeders through Prosumers Data Driven Forecasting and Model Predictive Control of Electrochemical Storage [PDF]

open access: yes, 2016
We propose and experimentally validate a control strategy to dispatch the operation of a distribution feeder interfacing heterogeneous prosumers by using a grid-connected battery energy storage system (BESS) as a controllable element coupled with a ...
Cherkaoui, Rachid   +3 more
core   +4 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Fuzzy Controller for Matrix Converter System to Improve its Quality of Output

open access: yes, 2010
In this paper, Fuzzy Logic controller is developed for ac/ac Matrix Converter. Furthermore, Total Harmonic Distortion is reduced significantly. Space Vector Algorithm is a method to improve power quality of the converter output.
Gurusamy, G., Mahendran, Nagalingam
core   +2 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

open access: yesAging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

Conventional Space-Vector Modulation Techniques versus the Single-Phase Modulator for Multilevel Converters [PDF]

open access: yes, 2010
Space-vector modulation is a well-suited technique to be applied to multilevel converters and is an important research focus in the last 25 years. Recently, a single-phase multilevel modulator has been introduced showing its conceptual simplicity and
Carrasco Solís, Juan Manuel   +6 more
core  

The Focal plane Detector Package on the TUNL Split-pole Spectrograph [PDF]

open access: yes, 2018
A focal plane detector for the Enge Split-pole Spectrograph at Triangle Universities Nuclear Laboratory has been designed. The detector package consists of two position sensitive gas avalanche counters, a gas proportionality energy loss section, and a ...
Champagne, Arthur E.   +7 more
core   +3 more sources

Advancing Research on Biomaterials and Biological Materials with Scanning Electron Microscopy under Environmental and Low Vacuum Conditions

open access: yesAdvanced Engineering Materials, EarlyView.
Herein, environmental scanning electron microscopy (ESEM) is discussed as a powerful extension of conventional SEM for life sciences. By combining high‐resolution imaging with variable pressure and humidity, ESEM allows the analysis of untreated biological materials, supports in situ monitoring of hydration‐driven changes, and advances the functional ...
Jendrian Riedel   +6 more
wiley   +1 more source

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