Results 101 to 110 of about 11,829 (297)

Mechanosensitive Piezo1/Osteocalcin/Irisin Axis Protects Against Disuse‐Induced Muscle Atrophy

open access: yesAdvanced Science, EarlyView.
Mechanical unloading suppresses bone Piezo1 expression, which reduces circulating undercarboxylated osteocalcin (unOCN). unOCN reduction subsequently exacerbates IMM‐induced Fndc5/Irisin decrease and drives severe muscle atrophy. Bone Piezo1 activation or exogenous osteocalcin/Irisin ameliorate muscle atrophy, while muscle‐specific Gprc6a or Fndc5 ...
Zhaolu Wang   +5 more
wiley   +1 more source

Történeti beszédaktus-kutatás: a középkori katalán plaure ’tetszik’ igével alkotott szerkezetekről [Diachronic speech act analysis: on some constructions with the verb plaure ‘please’ in medieval Catalan]

open access: yesJelentés és Nyelvhasználat, 2018
The primary aim of this paper is to reveal uses of medieval Catalan constructions with subjunctive forms of the verb plaure ‘please’. Relying on a large corpus of historical texts from the 13th to 16th centuries, I argue that they are highly ...
Nagy C. Katalin
doaj   +1 more source

Electrochemical Modulation of Laser‐Induced Covalent Functionalization of Graphene

open access: yesAdvanced Science, EarlyView.
Photoelectrochemical functionalization of graphene introduces the electrochemical potential as an additional parameter for the laser‐induced covalent modification of graphene. Tuning of the potential allows for amplification or suppression of the functionalization reaction with constant laser parameters, which enables in situ Raman analysis of ...
Tamara Nagel   +7 more
wiley   +1 more source

Analysis of an indirect speech act in a vertical functional structure in a department : Case study of A Company

open access: yes, 2015
Employees achieve efficiency in tasks in an organization through communication with trust and openness to one another. Failure in effective interaction in a team is one of the factors that derail a process to an organization’s mission. Types of obstacles
박세미
core  

In Vivo Electrochemical Monitoring of Safinamide Pharmacokinetics in the Brain Explores Its Correlation With Vision‐Related Neuronal Activity

open access: yesAdvanced Science, EarlyView.
An electrochemical platform based on differential pulse amperometry enables real‐time, selective tracking of safinamide pharmacokinetics in the living brain with high spatiotemporal resolution. When integrated with electrophysiology, this approach reveals that drug‐induced suppression of vision‐related neuronal activity provides mechanistic insight ...
Xiaoke Nan   +9 more
wiley   +1 more source

ANALISIS TERJEMAHAN TINDAK TUTUR MEMUJI (COMPLIMENT) PADA SUBTITLE FILM TWILIGHT SERIES DAN KUALITAS TERJEMAHANNYA

open access: yesPrasasti: Journal of Linguistics, 2017
The aims of the study are to analyze the translations of compliment in subtitle film Twilight Series  between source text (English) and target text (Indonesian).
Wahyudi Wahyudi   +2 more
doaj   +1 more source

A Humanized Anti‐gD Broadly Neutralizing Antibody Confers Complete Post‐Exposure Protection against Pseudorabies Virus

open access: yesAdvanced Science, EarlyView.
Pseudorabies virus (PRV), an emerging zoonotic α‐herpesvirus, causes life‐threatening human encephalitis. We identified a broad‐spectrum neutralizing antibody 6F7 targeting PRV gD. It blocks gD‐Nectin‐1 binding and membrane fusion, inhibiting replication across all PRV variants, representing a promising candidate for anti‐PRV therapy.
Yue Sun   +11 more
wiley   +1 more source

PlantGFM: A Genomic Foundation Model for Discovery and Creation of Plant Genes

open access: yesAdvanced Science, EarlyView.
A plant genomic foundation model pre‐trained on 12 species enables both accurate gene prediction and de novo gene design. Through AI‐human knowledge screening, seven designed sequences showed transcriptional activity in plants, with two expressing stable proteins—demonstrating the first DNA‐RNA‐protein expression of LLM‐generated genes in plants and ...
Changhao Li   +10 more
wiley   +1 more source

中国人日本語学習者はどのように間接発話行為を理解するのか

open access: yes, 2020
2020-03-31The present study examined the process of comprehension of indirect speech act by native Chinese speakers learning Japanese. I firstly improved the limitation of previous research and conducted a cloze test to measure 30 tester’s proficiency ...
LI, LU, 李, 璐
core   +1 more source

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