Results 141 to 150 of about 320,160 (346)

Indirect Speech Acts in the Speech of the Characters of the Tale of Bygone Years

open access: yesSlovene, 2017
The article states that communication in Old Russian as well as in modern Russian discourse is characterized by the use of mono-functional and poly-functional indirect speech acts.
Victor S. Savelyev
doaj  

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

open access: yesAdvanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang   +7 more
wiley   +1 more source

Going Viral: Vaccines, Free Speech, and the Harm Principle [PDF]

open access: yes, 2016
This paper analyzes the case of public anti-vaccine campaigns and examines whether there may be a normative case for placing limitations on public speech of this type on harm principle grounds.
Unterreiner, Miles
core  

Biomimetic Membrane Interface Technologies for Detection and Isolation of CTCs and EVs: Advances and Opportunities in Liquid Biopsy

open access: yesAdvanced Science, EarlyView.
Biomimetic membrane interface engineering constructs functionalized detection platforms by integrating natural cell membranes, synthetic lipids, or hybrid membranes. This strategy effectively reduces background interference and enables efficient target capture and analysis, showing broad applications in circulating tumor cell separation, extracellular ...
Duo Liu   +8 more
wiley   +1 more source

Pragmatic Failures in Intercultural Communication: Evidence from Jordan

open access: yesПсихолінгвістика
Aim. This paper investigates the pragmatic errors of Jordanian EFL learners from a cultural perspective on communication. It is suggested that pragmatics, or the study of how language is used in context, plays a crucial role in L2 learners’ communicative
Абдель Рахман Алтахіне   +2 more
doaj   +1 more source

Speech Acts: The Contemporary Theoretical Landscape [PDF]

open access: yes, 2018
What makes it the case that an utterance constitutes an illocutionary act of a given kind? This is the central question of speech-act theory. Answers to it—i.e., theories of speech acts—have proliferated.
Fogal, Daniel   +2 more
core  

Higher‐Level Structural Classification of Pseudomonas Cyclic Lipopeptides through Their Bioactive Conformation

open access: yesAdvanced Science, EarlyView.
Solution structures of a series of cyclic lipodepsipeptides from Pseudomonas reveal that these specialized metabolites adopt left‐handed alpha helical conformations of only two types, being either ‘stapled’ or ‘catch‐pole’ helix. The particular modular distribution of the biosynthetic gene clusters is found to determine the extent of their conserved ...
Benjámin Kovács   +9 more
wiley   +1 more source

The syntax of orientation shifting: Evidence from English high adverbs [PDF]

open access: yes, 2014
This paper reviews new data supporting the inclusion of a Speech Act Phrase in the left periphery. Illocutionary and evidential adverbs in English shift orientation from speakers in declarative sentences to addressees in yes-no interrogative sentences ...
Woods, Rebecca
core  

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

open access: yesAdvanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li   +7 more
wiley   +1 more source

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