Results 51 to 60 of about 189,665 (265)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Islamic Counseling: Jurnal Bimbingan Konseling IslamThis research aims to describe the implementation stages of individual counseling using a behavioral approach for perpetrators of sexual violence at the UPTD PKS Insan Berguna, Lampung Province Social Service.
Risma Fitriyanti +2 more
doaj +1 more source
The Analysis of the Individual Counseling at Student Counseling Center
Psihologijske teme, 1999 Studentski savjetovališni centar (SSC) pri Odsjeku za psihologiju Filozofskog fakulteta u Rijeci djeluje od siječnja 1998. godine. Tijekom dvogodišnjeg razdoblja na individualno savjetovanje javilo se 82 studenta (74% djevojaka i 26% mladića). Za 92% studenata to je bilo prvo mjesto na koje su se obratili tražeći pomoć. Na temelju analize problema koje
Smojver Ažić, Sanja +2 more
openaire
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Jurnal Kajian Bimbingan dan Konseling, 2018 : The purpose of this study was to evaluate school counselor performance in organizing individual counseling services using self evaluation and peer evaluation. This study uses descriptive survey approach through descriptive comparative study.
Muya Barida, Sutarno Sutarno
doaj
Psikopedagogia: Jurnal Bimbingan dan Konseling, 2016 This study aimed to describe the students' perception of guidance and counseling teachers in the implementation of individual counseling services. This research is descriptive quantitative with data collection instruments in the form of a questionnaire ...
Dian Putri Rachmadhani
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source