Results 111 to 120 of about 11,596,501 (293)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

PROBLEMS OF IMPLEMENTATION AND HARMONIZATION OF INDIVIDUAL AND CORPORATE INTEREST

open access: yesВестник университета, 2019
Discusses the issue of coordination of interests of participants of economic activities. The designated subjects of the market relations that serve as the basis for the implementation of the market transactions, which are implemented and economic ...
D. Gurov, N. Gotskay
doaj  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Faktor-Faktor yang Mempengaruhi Rendahnya Minat Siswa Memanfaatkan Layanan Konseling Perorangan

open access: yesIndonesian Journal of Guidance and Counseling: Theory and Application, 2013
Tujuan penelitian ini untuk mengetahui faktor-faktor yang mempengaruhi rendahnya  minat siswa kelas VIII dan IX di SMP N 1 Sigaluh Banjarnegara tahun pelajaran 2012/ 2013 dalam memanfaatkan layanan konseling perorangan.
Tyas Prastiti   +2 more
doaj  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

The Hierarchy of Interests as a Decision-Making Criterion in the NIMBY Situation

open access: yesStudia Regionalne i Lokalne
Decision-making in a conflict situation in public policy practice is most often associated with conflicts of interest. One of the frequent forms of this conflict is the so-called NIMBY phenomenon, which has become a subject of interest mainly because of ...
Stanislav Konečný
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Exploring the categories of students’ interest and their relationships with deep learning in technology supported environments

open access: yesScientific Reports
Interest is not only the starting point to begin a wonderful learning journey for students, but also an important driver for deep learning and continuous progress.
Jiawei Guo, Fuhai An
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

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