Results 161 to 170 of about 11,596,501 (293)

Dynamic complexity of moral motivation: the roles of duty and self-interest. [PDF]

Front Psychol
Kaplan U.
europepmc   +1 more source

Special Interest Melbourne Walking Tour (TOU20003 Special Interest Tourism)

, 2016
This video will assist students with their TOU20003-Special Interest Tourism walking tour assessment ...
Ryan Jopp, David Yammouni
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Protocol for the development of a paediatric core outcome set for arthrogryposis multiplex congenita: an international multi-interest-holder consensus study. [PDF]

BMJ Open
Zukerman N, Darsaklis VB, Araujo C, Cachecho S, Costa C, Donlevie K, Fąfara A, Kasar U, Krakie C, Lacombe F, Pacey V, Sions JM, Dahan-Oliel N.   +12 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Institutional conflicts of interest in health-related research - a scoping review. [PDF]

Res Integr Peer Rev
Haarmann A, Kugler CM, Goodarzi H, Pachanov A, Goossen K, Akl EA, Pieper D.   +6 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Research Capacity and Culture of Podiatrists in Canada (Quebec) and France: A Parallel Cross-Sectional Study. [PDF]

J Foot Ankle Res
Libier S, Ghio SC, Perrier A, Brousseau-Foley M, Lazzarini P, Blanchette V.   +5 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Linking social attention to reproductive state and future reproduction in female monkeys. [PDF]

Behav Ecol Sociobiol
Hernández-Pacheco R, Diaz AA, Aiempichitkijkarn N, Peña NC, Yahyazadehmoghaddam S, Weber J, Maldonado E, Tuljapurkar S, Rosati AG.   +8 more
europepmc   +1 more source