Results 61 to 70 of about 6,787,479 (245)

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Mobile augmented reality in support of building damage and safety assessment [PDF]

Natural Hazards and Earth System Sciences, 2016
Rapid and accurate assessment of the state of buildings in the aftermath of a disaster event is critical for an effective and timely response. For rapid damage assessment of buildings, the utility of remote sensing (RS) technology has been widely ...
W. Kim, N. Kerle, M. Gerke
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Detection of Depressive Symptoms in College Students Using Multimodal Passive Sensing Data and Light Gradient Boosting Machine: Longitudinal Pilot Study

JMIR Formative Research
BackgroundDepression is the top contributor to global disability. Early detection of depression and depressive symptoms enables timely intervention and reduces their physical and social consequences.
Jessica L Borelli, Yuning Wang, Frances Haofei Li, Lyric N Russo, Marta Tironi, Ken Yamashita, Elayne Zhou, Jocelyn Lai, Brenda Nguyen, Iman Azimi, Christopher Marcotullio, Sina Labbaf, Salar Jafarlou, Nikil Dutt, Amir Rahmani   +14 more
doaj   +1 more source

Inferring transportation mode from smartphone sensors: Evaluating the potential of Wi-Fi and Bluetooth.

PLoS ONE, 2020
Understanding which transportation modes people use is critical for smart cities and planners to better serve their citizens. We show that using information from pervasive Wi-Fi access points and Bluetooth devices can enhance GPS and geographic ...
Andreas Bjerre-Nielsen, Kelton Minor, Piotr Sapieżyński, Sune Lehmann, David Dreyer Lassen   +4 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

An Integrated Mobile Robot Framework for Worker Safety, Defect, and Thermal Monitoring in Construction

Applied Sciences
Accurate sensing is essential for automated inspection in complex construction environments. This study develops and field-validates an integrated mobile-robot framework combining worker localization, structural crack detection, and thermal monitoring ...
Taehun Choi, Sejun Jang, Jaemin Jeong
doaj   +1 more source

A UAV-assisted Multi-task Allocation Method for Mobile Crowd Sensing

, 2022
Mobile crowd sensing (MCS) has been widely used as a cost-efcient way to collect data for smart cities, which typically starts with participant recruitment and task allocation.
Xiao, Yu, Gao, Hui, Feng, Jianhao, Zhang, Bo, Wang, Wendong, Bo Zhang, Jianhao Feng, Yu Xiao, Wendong Wang, Hui Gao   +9 more
core   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source