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Body-mass index and all-cause mortality: individual-participant-data meta-analysis of 239 prospective studies in four ...
John Potter +2 more
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Individual Participant Data Meta-Analyses Should Not Ignore Clustering
Individual participant data (IPD) meta-analyses often analyze their IPD as if coming from a single study. We compare this approach with analyses that rather account for clustering of patients within studies.Comparison of effect estimates from logistic regression models in real and simulated examples.The estimated prognostic effect of age in patients ...
Richard D. Riley +2 more
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Individual Participant Data (IPD) Meta-Analysis
2021Individual participant data (IPD) meta-analyses are relatively new compared with the traditional aggregate data meta-analyses. IPD meta-analyses involve the collection, checking, and re-analysis of the original data for each participant in each study.
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An individual participant data meta-analysis
2021Objective: Behavioral interventions are well established treatments for children with attention-deficit/hyperactivity disorder (ADHD). However, insight into moderators of treatment outcome is limited. Method: We conducted an individual participant data meta-analysis (IPDMA), including data of randomized controlled behavioral intervention trials for ...
Groenman, Annabeth P. +33 more
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Efficient integration of aggregate data and individual participant data in one‐way mixed models
Statistics in Medicine, 2022Often both aggregate data (AD) studies and individual participant data (IPD) studies are available for specific treatments. Combining these two sources of data could improve the overall meta‐analytic estimates of treatment effects. Moreover, often for some studies with AD, the associated IPD maybe available, albeit at some extra effort or cost to the ...
Neha Agarwala, Junyong Park, Anindya Roy
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Meta-Analysis of a Binary Outcome Using Individual Participant Data and Aggregate Data
Research Synthesis Methods, 2010Abstract In this paper, we develop meta‐analysis models that synthesize a binary outcome from health‐care studies while accounting for participant‐level covariates. In particular, we show how to synthesize the observed event‐risk across studies while accounting for the within‐study association between participant‐level covariates and ...
Richard D. Riley, Ewout W. Steyerberg
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Overcoming obstacles in obtaining individual participant data for meta‐analysis
Research Synthesis Methods, 2016Individual participant data (IPD) is the backbone of scientific inquiry and important to a meta‐analysis for a variety of reasons. It is therefore important to be able to access IPD, and yet, obstacles persist that make it difficult for meta‐analysts, as well as interested primary study analysts, to obtain it.
Joshua R, Polanin, Ryan T, Williams
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