Results 41 to 50 of about 32,743,025 (287)

Meta-analysis using individual participant data: one-stage and two-stage approaches, and why they may differ. [PDF]

, 2016
Meta-analysis using individual participant data (IPD) obtains and synthesises the raw, participant-level data from a set of relevant studies. The IPD approach is becoming an increasingly popular tool as an alternative to traditional aggregate data meta ...

core   +1 more source

Hydroxychloroquine in the Pregnancies of Women with Lupus: A Meta-Analysis of Individual Participant Data [PDF]

Lupus Science & Medicine, 2021
Abstract Objective Multiple guidelines recommend continuing hydroxychloroquine (HCQ) for systemic lupus erythematosus (lupus) during pregnancy based on observational data. The goal of this individual patient data meta-analysis was to combine multiple datasets to compare pregnancy outcomes in women ...
Megan E B Clowse, Amanda M Eudy, Stephen Balevic, Gillian Sanders-Schmidler, Andrzej Kosinski, Rebecca Fischer-Betz, Dafna D Gladman, Yair Molad, Cecilia Nalli, Abir Mokbel, Angela Tincani, Murray Urowitz, Caroline Bay, Megan van Noord, Michelle Petri   +14 more
openaire   +5 more sources

Quantifying heterogeneity in individual participant data meta-analysis with binary outcomes

Systematic Reviews, 2017
Background In meta-analyses (MA), effect estimates that are pooled together will often be heterogeneous. Determining how substantial heterogeneity is is an important aspect of MA.
Bo Chen, Andrea Benedetti
doaj   +1 more source

Benefits and harms of Risperidone and Paliperidone for treatment of patients with schizophrenia or bipolar disorder: a meta-analysis involving individual participant data and clinical study reports

BMC Medicine, 2021
Background Schizophrenia and bipolar disorder are severe mental illnesses which are highly prevalent worldwide. Risperidone and Paliperidone are treatments for either illnesses, but their efficacy compared to other antipsychotics and growing reports of ...
Alexander Hodkinson, Carl Heneghan, Kamal R. Mahtani, Evangelos Kontopantelis, Maria Panagioti   +4 more
doaj   +1 more source

Self-Help Plus for refugees and asylum seekers: an individual participant data meta-analysis

BMJ Mental Health, 2023
Question Refugees and asylum seekers are at high risk of mental disorders due to various stressors before, during and after forceful displacement. The WHO Self-Help Plus (SH+) intervention was developed to manage psychological distress and a broad range ...
Eirini Karyotaki, Pim Cuijpers, Maritta Välimäki, Marianna Purgato, Kenneth Carswell, Ceren Acarturk, Teresa Au, Minna Anttila, Della Bailey, Rachel Churchill, Markus Koesters, Tella Lantta, Mariana Popa, Marit Sijbrandij, Federico Tedeschi, Ersin Uygun, Johannes Wancata, Corrado Barbui, Mark Van Ommeren, Wietse A Tol, Ross G White, Daniel Lakin, Emily Peckham, Jura Augustinavicius, Marx Ronald Leku, Sarah Al-Hashimi, Thomas Klein   +26 more
doaj   +1 more source

Resource implications of preparing individual participant data from a clinical trial to share with external researchers

Trials, 2017
Background Demands are increasingly being made for clinical trialists to actively share individual participant data (IPD) collected from clinical trials using responsible methods that protect the confidentiality and privacy of clinical trial participants.
Catrin Tudur Smith, Sarah Nevitt, Duncan Appelbe, Richard Appleton, Pete Dixon, Janet Harrison, Anthony Marson, Paula Williamson, Elizabeth Tremain   +8 more
doaj   +1 more source

Individual participant data (IPD) meta-analysis: An introduction – Narrative review

Indian Journal of Anaesthesia
Systematic reviews and meta-analyses (MA) are accepted modalities for evidence synthesis in evidence-based medicine. However, as MA uses aggregate data that includes averaging patient characteristics and pooled effect estimates, it has limitations when ...
Ekta Rai, Vibhavari Naik, Aparna Williams, Mohan S. Kamath   +3 more
doaj   +1 more source

Meta-analysis of individual participant data: rationale, conduct, and reporting [PDF]

BMJ, 2010
The use of individual participant data instead of aggregate data in meta-analyses has many potential advantages, both statistically and clinically. Richard D Riley and colleagues describe the rationale for an individual participant data meta-analysis and outline how to conduct this type of study Meta-analysis methods involve combining and analysing ...
Riley, RD, Lambert, PC, Abo-Zaid, G
openaire   +3 more sources

Distribution of summary measures of physical activity data at individual participant level.

, 2023
Distribution of summary measures of physical activity data at individual participant level.
Michael Thelwell (11668833), Helen Dawes (108846), Christopher Burton (328387), Simon Goodwill (12455502), Caroline Dalton (8334342)   +4 more
core   +1 more source

Bridging the Loneliness Gap: Depression, Connectivity, and Isolation in Pediatric Oncology Patients and Their Peers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld, Scott H. Maurer, Michelle D. Watkinson, John Nury, Elise Barberis, Molly C. Mack   +5 more
wiley   +1 more source