Results 121 to 130 of about 1,150,811 (289)

Congolese Children and Youth: USCCB Network Unaccompanied Refugee Minor Program Experiences and Implications [PDF]

, 2013
While over thousands of Congolese have resettled through the adult resettlement program, the USCCB network has assisted a smaller number of approximately 100 children and youth between 2007 through early 2013.
Nathalie Lummert
core  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Trying to Become the Person I Was Before: 9/11 Displaced Workers and the Employment Assistance Program [PDF]

, 2005
This report examines the September 11th Fund's Employment Assistance Program (EAP), an effort to enable workers displaced by the 9/11 terrorist attacks to connect with employment services, career counselors, job placement opportunities, education ...
Bonny Fraser, Kathy Krepcio, Ronnie Kauder, Scott Reynolds   +3 more
core  

Illuminating Undergraduate Experiential and Situated Learning in Podiatry Clinical Placement Provision at a UK School of Podiatric Medicine [PDF]

, 2019
Purpose Situated and experiential learning methodologies are largely under researched in relation to student experience and satisfaction. This research aimed to illuminate the perspectives of students studying on a BSc (Hons) Podiatry degree programme ...
Bussey, Sonia, Graham, Yitka, Hayes, Catherine   +2 more
core   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Study protocol and preliminary baseline characteristics of a VA multi-site, mixed methods, randomized controlled study evaluating supported employment provided to veterans with opioid use disorder

Annals of General Psychiatry
Opioid Use Disorder (OUD) is a pervasive and devastating public health crisis that continues to take a heavy toll on individuals and communities across the United States. In 2021, approximately 473,000 veterans misused opioids in the past year.
Mercy Mumba, Teresa Granger, George Mugoya, Stephen Brackett, Junfei Lu, Emily Lund, Charles Lynn, Anchal Ghera, Whitney Gay, Lori Davis   +9 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Multidirectional chromosome painting substantiates the occurrence of extensive genomic reshuffling within Accipitriformes. [PDF]

, 2015
BACKGROUND: Previous cross-species painting studies with probes from chicken (Gallus gallus) chromosomes 1-10 and a paint pool of nineteen microchromosomes have revealed that the drastic karyotypic reorganization in Accipitridae is due to extensive ...
Beiyuan Fu, Bertrand Bed’Hom, Fengtang Yang, Gauthier Dobigny, Jinghuan Wang, Kai He, Malcolm A. Ferguson-Smith, Patricia C. M. O’Brien, Vitaly Volobouev, Weiting Su, Wenhui Nie   +10 more
core   +4 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

PATHWAYS TO WORK AND WELLBEING: EMPLOYMENT PREDICTORS AND CHANGES IN HEALTH AND WELLBEING IN INDIVIDUALS PARTICIPATING IN THE INDIVIDUAL PLACEMENT AND SUPPORT PROGRAMME [PDF]

Psychiatria Fennica
Background: IPS (Individual Placement and Support) programme is an evidence-based practice to promote the employment of people with severe mental health disorders in the competitive labour market.
NOORA SIPILÄ, KAIJA APPELQVIST-SCHMIDLECHNER
doaj