Results 61 to 70 of about 1,643,276 (299)

Urban foraging : individual variation in inner-city graffiti writers' target preferences and specialization [PDF]

open access: yes, 2020
Objectives: Drawing upon optimal foraging theory, we examine graffiti writers’ individual target preferences to establish the diversity in their target choices (henceforth called “target specialization”).
Lens, Luc   +3 more
core   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Are completed ReSPECT plans facilitating person-centred care? An evaluation of completed plans in UK general practice

open access: yesResuscitation Plus
Background: The Recommended Summary Plan for Emergency Care and Treatment (ReSPECT) includes agreed clinical recommendations for a person’s care in a future emergency which have been informed by discussion of the person’s preferences. Previous evaluation
Caroline J. Huxley   +9 more
doaj   +1 more source

Social preferences, accountability, and wage bargaining [PDF]

open access: yes, 2012
We assess the extent of preferences for employment in a collective wage bargaining situation with heterogeneous workers. We vary the size of the union and introduce a treatment mechanism transforming the voting game into an individual allocation task ...
A Falk   +47 more
core   +2 more sources

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Contextual perceived group threat and radical right-wing populist party preferences: Evidence from Switzerland

open access: yesResearch & Politics, 2016
Existing studies suggest that perceived group threat is an important influence on radical right-wing populist party preferences. However, most have focused on perceived group threat at the individual level, overlooking the ideological climate.
Carl C. Berning
doaj   +1 more source

Individual preferences and social interactions determine the aggregation of woodlice. [PDF]

open access: yesPLoS ONE, 2011
The aggregation of woodlice in dark and moist places is considered an adaptation to land life and most studies are focused on its functionality or on the behavioural mechanisms related to the individual's response to abiotic factors.
Cédric Devigne   +2 more
doaj   +1 more source

Voice pitch preferences of adolescents: Do changes across time indicate a shift towards potentially adaptive adult-like preferences? [PDF]

open access: yes, 2013
An evolutionary approach to attractiveness judgments emphasises that many human trait preferences exist in order to assist adaptive mate choice. Here we test an adaptive development hypothesis, whereby voice pitch preferences indicating potential mate ...
DeBruine, Lisa   +4 more
core   +4 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

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