Results 71 to 80 of about 256,716 (310)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Emotional burnout characteristics of Lithuanian individual sports coaches.
, 2014 Object of research: Emotional burnout of Lithuanian individual sports coaches. Scientific problem of research: There are no studies about Lithuanian individual sports coaches emotional burnout characteristics, do coaches experiencing emotional burnout ...
Barauskaitė, Dominyka,
core
Exercise and Quality of Life, 2013 The purpose of the present study was to examine the anthropometric parameters and cardiopulmonary functions of young handball players in different playing positions.
Alexandra Cselkó +3 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Management of and Potential Return on Private Investments in Latvian Sports
, 2017 Background. Latvian sports authorities under the Ministry of Education and Science are the main organisers of the sports life in Latvia. However, they have not been successful in providing equally good support to all athletes who need it.
Lauva, Mārtiņš, Grāvītis, Uldis
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Turkish Journal of Kinesiology, 2016 The aim of this study is to investigate the contribution ratios of Growth rates and specific motor abilities as a function to predict the selection of talented taekwondo sport.
Mohammed Mustafa Bakr
doaj +2 more sources
World Ranking of Female Judokas and its Relation to Results of Paris Olympic Games 2024 [PDF]
Assiut Journal of Sport Science and ArtsObjective: The research aimed to identify the relationship between the ranking of female judokas in the World Ranking List (WRL) and the results of the Paris 2024 Olympic Games.
Mahmoud E. Baioumy +2 more
doaj +1 more source