Results 141 to 150 of about 20,150 (254)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Human dignity and ontological foundations: a philosophical perspective for the health professions. [PDF]

Philos Ethics Humanit Med
Frantz P, Rego F, Barbas S.
europepmc   +1 more source

FREEDOM AS CO-EXISTENCE IN A COMMUNITY

, 1998
Hegelovo je učenje o objektivnom duhu, kao momentu svjetskog duha, ideja koja počiva na temelju objektivne ćudorednosti, a moderna je država najviši povijesni pojavni oblik te ćudorednosti.
Goran Gretić, Gretić, Goran
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

A structured analysis of the concept of brain death. [PDF]

Theor Med Bioeth
Beckmann RJ.
europepmc   +1 more source

Transformation and growth : the Davidic temple builder in Ephesians

, 2012
The focus of this thesis is on the way in which the theology of the author of the Epistle to the Ephesians is both shaped by and shapes the appropriation of OT texts and themes, especially in Eph 2:11-22.
Stirling, A. Mark
core  

The Role of Socio-cultural Relations in Forming Community Perceptions of Geothermal Energy Existence in Lahendong, North Sulawesi, Indonesia

Lahendong Village of the Tomohon Municipal is one of the geothermal energy-producing areas in North Sulawesi, Indonesia. Geothermal energy has been a part of Lahendong people's daily life for hundreds of years.
Pri Utami, Fitria Yusrifa, Siti Murtiningsih   +2 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

The Conception of Existence According to Mieczyslaw Gogacz. A Contribution to the History of Consequential Thomism’s Formation

, 2016
The concept of existence (esse) as an act of making realistic and actual individual being describes the basic feature of Consequential Thomism which refers to all possible philosophical analysis from the topic of existence (esse), because existence (esse)
Andrzejuk, Artur
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source