Results 111 to 120 of about 47,537 (316)

Who Is (Not) Individual: Individualism, Individuality, and Negation

open access: yes, 2020
Relying on a scene from Monty Python's Life of Brian movie, the article would indicate the characteristically modern dilemmas in the understanding of the category of individual. The speech which Brian delivers to his assembled followers, and the reactions to it, amusingly display typical conceptual problems arising in both, the contemporary crucial and
openaire   +1 more source

Dutch decision as rooted in Dutch culture: An ethnologic study of the Dutch decision process [PDF]

open access: yes
Consensus is a mode of regulation well adapted to globalisation as it provides a means to reach agreements and manage diversity at the same time. However, is it a universal decision mode?
Jacqueline De Bony
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Self or group? Individualism-collectivism influences on feedback effects [PDF]

open access: yes, 2004
One dimension of culture-individualism and collectivism was investigated to test hypotheses that for individualists, individual feedback would have a stronger impact on performance than collectivists and vice versa., a 2×2 between subjects design (type ...
K. Shi, Y. L. Wang
core  

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Group-Oriented Values, Rules and Cooperation [PDF]

open access: yes
collectivism, cooperation, economic development, game theory, individualism, institutions ...
Chu, Ke-young
core  

Cultural Influences on the Formation of Interpersonal Intentions [PDF]

open access: yes, 2004
The formation of interpersonal intentions has been a central theme in socialpsychological research for over twenty years. Existing psychological models propose that attitudes, social norms, and moral obligations often combine to form intentions.
Polanco, Susan
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Individual Home Advantage with Individual Data

open access: yes, 2021
Home advantage (HA) is a well-documented phenomenon in (professional) team sports. However, there is also a growing body of evidence that in individual sports home athletes have an advantage. I define HA as ‘the performance advantage of an athlete, team, or country when they compete at a home ground compared to their performance under similar ...
openaire   +2 more sources

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