Results 51 to 60 of about 308,507 (245)
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Something, nothing : space, substance, and sexual identity in Shakespeare [PDF]
This paper argues that early, "preoedipal" anxieties about dependency, autonomy, the boundaries of the self, the dangerous interpenetration of inner and outer worlds--the outer world contaminating the inner self, the self afraid of losing the precious
Splitter, Randolph
core
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Hofstede’s Cultural Dimensions and Tourist Behaviors: A Review and Conceptual Framework [PDF]
This paper develops a conceptual framework for analyzing tourist behaviors and identifies three categories of behaviors based on the applications of Hofstede’s cultural dimensions and the processes underlying these influences.
Manrai, Ajay K., Manrai, Lalita A.
core
Conflict Resolution: Cultural Understanding Imperative [PDF]
Business transactions and other potential incidences of conflict resolution must be met by participants who have transcended the isolating and often arrogant traits of individualism and must expand to embrace the collective — to realize the importance of
Tindal, Livingston S
core +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Living in the garden of Eden: Mineral resources foster individualism [PDF]
Using mineral resources discoveries in the United States since 1800, we argue that mineral mining fosters individualism. Measuring individualism and the demand for redistribution by questions of the General Social Survey (GSS), we show that: (i ...
Marc Sangnier, Mathieu Couttenier
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
A century of methodological individualism part 1: Schumpeter and Menger [PDF]
2009 marks the centenary of methodological individualism (MI). The phrase was first used in English in a 1909 QJE paper by Joseph Schumpeter. Yet after 100 years there is considerable confusion as to what the phrase means.
Denis, A.
core

