Results 81 to 90 of about 47,537 (316)
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Individualism in international relations is a theoretical perspective which emphasizes the role and agency of individual actors, particularly states, in shaping the dynamics and outcomes of world politics.
Pranzo, Diane Marie
core +1 more source
Neo-Liberal individualism or self-directed support : are we all speaking the same language on modernising adult social care. [PDF]
This article explores recent developments in the modernisation of adult social care through the lens of changes to English day services. Drawing on wider policy debates, it argues that Disabled Peoples’ Movement and governmental ideas on self-directed ...
Roulstone, A. +5 more
core +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Investigation of Methodological Individualism and its Challenges in Social Sciences
The aim of this paper is to investigate the view of methodological individualism towards explanation of social phenomena. This view explains social phenomena in terms of individual actions.
Mohammadtaghi Iman +1 more
doaj
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Individualism-collectivism: reconstructing Hofstede’s dimension of cultural differences [PDF]
Individualism-Collectivism (I-C), a key concept in cross-cultural research and one of the most studied context variables in personality, social, and developmental psychology, is often treated as synonymous with Hofstede’s pioneering nation scores ...
Christian Welzel (778973) +3 more
core

