Results 91 to 100 of about 355,662 (382)
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Psychologists' social representations of conformity: Conformity – birth or death of individuality [PDF]
When discussing conformity, modern social psychological literature draws its conclusions mostly from the classical sources written by the mid twentieth century authors such as Muzafer and CarolynSherif, Leon Festinger, Solomon Asch, Morton Deutsch, and ...
Janez Bečaj
doaj
Movement vigor as a traitlike attribute of individuality.
A common aspect of individuality is our subjective preferences in evaluation of reward and effort. The neural circuits that evaluate these commodities influence circuits that control our movements, raising the possibility that vigor differences between ...
T. Reppert+5 more
semanticscholar +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Nutrition can have significant effects on behavior and cognitive processes. Most of the studies related to this use extremely modified diets, such as high fat contents or the exclusion of distinct components needed for normal development and bodily ...
Jovana Maliković+6 more
doaj +1 more source
Reconsidering Public Relations’ Infatuation with Dialogue: Why Engagement and Reconciliation Can Be More Ethical Than Symmetry and Reciprocity [PDF]
Advocates of dialogic communication have promoted two-way symmetrical communication as the most effective and ethical model for public relations. This article uses John Durham Peters’s critique of dialogic communication to reconsider this infatuation ...
Berg, Kati Tusinski, Stoker, Kevin L.
core +1 more source
Measuring Transcription at a Single Gene Copy Reveals Hidden Drivers of Bacterial Individuality
Single-cell measurements of mRNA copy numbers inform our understanding of stochastic gene expression1–3, but these measurements coarse-grain over the individual copies of the gene, where transcription and its regulation take place stochastically4,5. Here,
Mengyu Wang+3 more
semanticscholar +1 more source
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze+3 more
wiley +1 more source
Croatian Philosophers III: Pavao Vuk-Pavlović (1894–1976) [PDF]
The paper is a brief outline of Vuk-Pavlović’s life, his scholarly career and his philosophy. A short account of Vuk-Pavlović’s critique of the theory of knowledge and its interpretation as a meta-empirical issue is given, as well as some aspects of his ...
Lovorka Madjarevic
doaj