Results 211 to 220 of about 60,756 (303)

Navigating Treatment Selection in Acute Severe Ulcerative Colitis: A Prospective Mixed Method Analysis of Factors Influencing Patient Decision-Making. [PDF]

Dig Dis Sci
Herran R, Wilcox S, Hodish G, Hassan SA, Mertens H, Almario CV, Gu P, Kayal M, Cohen-Mekelburg S, Regal RE, Bishu S, Siegel CA, DeJonckheere M, Higgins PDR, Berinstein JA.   +14 more
europepmc   +1 more source

Transformer‐Based PET/CT Fusion Enables Preoperative Prediction and Prognostic Stratification of Spread Through Air Spaces in Lung Adenocarcinoma

Advanced Science, EarlyView.
An eight‐stream 2.5D Transformer integrates complementary PET metabolic and CT morphologic information to estimate spread‐through‐air‐spaces risk before surgery in lung adenocarcinoma. The model generalizes across independent centers, while its continuous risk score independently stratifies progression‐free survival, supporting further prospective ...
Xin‐Yu Zhu, Meng Meng, Zhen‐Zhen Wang, Deng‐Lu Lu, Ya‐Min Wei, Xu‐Chang Mi, Xing‐Yu Mu, Wei Fu   +7 more
wiley   +1 more source

Fluidity in filial piety: twenty-year associations of living arrangements on depression and life satisfaction and across chronic diseases among older adults in rural China. [PDF]

BMC Geriatr
Guo J, Wister A, Mitchell B, Silverstein M, Li S.   +4 more
europepmc   +1 more source

CausalCellInfer: Prioritizing Cell‐Type‐Specific Disease Associations From Genetically Predicted Transcriptomes in Biobank Cohorts

Advanced Science, EarlyView.
Bulk and genotype‐imputed transcriptomes obscure the cellular drivers of complex disease. CausalCellInfer resolves them by integrating invariant marker selection, deep learning deconvolution, and regularized matrix completion. Applied to ∼500 000 UK Biobank participants across 29 traits, it uncovers hallmark cell‐type proportion shifts, including ...
Liangying Yin, Yujia Shi, Ruoyu Zhang, Yong Xiang, Jinghong Qiu, Pak‐Chung Sham, Hon‐Cheong So   +6 more
wiley   +1 more source

Mitochondrial Quality Control in Degenerative Musculoskeletal Diseases: Signaling Networks and Therapeutic Landscapes

Advanced Science, EarlyView.
Mitochondrial quality control (MQC) collapse redefines osteoarthritis, intervertebral disc degeneration, and osteoporosis as disorders of organelle dysfunction. Damaged mitochondria leak mtDNA and metabolites, driving cGAS‐STING inflammation, epigenetic reprogramming, and metabolic memory.
Haiyang Gao, Zhangrong Cheng, Xianglong Chen, Wenbo Wu, Wang Wu, Zimu Yu, Cao Yang, Yukun Zhang   +7 more
wiley   +1 more source

Data-driven head model individualization from digitized electrode positions or photogrammetry improves M/EEG source localization accuracy. [PDF]

Imaging Neurosci (Camb)
Harmening N, von Lühmann A, Blankertz B.   +2 more
europepmc   +1 more source

Voluntary Collective Action to Address Growing Agricultural Challenges in Two Countries: Experimental Insights and Commonalities

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT We conducted two framed field economic experiments with citrus farmers in Florida, United States and soybean farmers in Argentina to investigate their willingness to coordinate pest and weed management efforts. Despite the contrast between these two agricultural contexts, we find striking behavioral commonalities.
Ariel Singerman, Sergio H. Lence
wiley   +1 more source

Effects of Velocity-Based Resistance Training on Renal Function and Metabolic Health in Kidney Transplant Recipients: Protocol for a Pilot Randomized Controlled Trial. [PDF]

JMIR Res Protoc
Peña Ibagon JC, Vasquez Osorio F, Collazos Morales CA, Tovar BE, Martin WF, Pardo YR, Tellez LA.   +6 more
europepmc   +1 more source

Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities

AGING MEDICINE, EarlyView.
Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley   +1 more source

European Society of Intensive Care Medicine Clinical Practice Guideline on fluid therapy in adult critically ill patients: A path toward improved patient management. [PDF]

J Intensive Med
De Backer D, Cecconi M, Ostermann M.
europepmc   +1 more source