Results 21 to 30 of about 130,066 (238)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

A nonparametric approach for model individualization in an artificial pancreas [PDF]

open access: yes, 2015
The identification of patient-tailored linear time invariant glucose-insulin models is investigated for type 1 diabetic patients, that are characterized by a substantial inter-subject variability.
Cobelli, Claudio   +5 more
core   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

From the Ne’er-Do-Well to the Criminal History Category: The Refinement of the Actuarial Model in Criminal Law [PDF]

open access: yes, 2003
Harcourt discusses three developments in 20th century criminal law: the evolution of parole board decision-making in the early 20th century, the development of fixed sentencing guidelines in the late 20th century, and the growth of criminal profiling as ...
Harcourt, Bernard E.
core   +2 more sources

Individual Risk [PDF]

open access: yesThe Journal of Clinical Hypertension, 2012
J Clin Hypertens (Greenwich). 2012;14:261–264. ©2012 Wiley Periodicals, Inc.Patients don’t have an “individual risk” or unique probability of an outcome. Outside Mendelian inheritance, risks are conditional probabilities and differ as the risk factors included differ, at times substantially. This lack of reliability is an inherent limitation and is not
openaire   +3 more sources

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

open access: yesAging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath   +3 more
wiley   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha   +4 more
wiley   +1 more source

EFEKTIVITAS PENERAPAN MODEL PEMBELAJARAN KOOPERATIF METODE JIGSAW DAN TEAM ASSISTED INDIVIDUALIZATION (TAI) TERHADAP PEMAHAMAN KONSEP SISWA: Studi Kuasi Eksperimen Pada Mata Pelajaran Ekonomi Standar Kompetensi (SK) Memahami Uang dan Perbankan Kelas X SMAN 1 Parongpong [PDF]

open access: yes, 2016
Tujuan penelitian ini adalah untuk menguji efektivitas penerapan metode Jigsaw dan metode Team Assisted Individualization (TAI) terhadap pemahaman konsep siswa.
Afritesya, Fitrah
core  

Psy-expertise, therapeutic culture and the politics of the personal in development [PDF]

open access: yes, 2017
Expertise stemming from the psy disciplines is increasingly and explicitly shaping international development policy and practice. Whilst some policy makers see the use of psy expertise as a new way to reduce poverty, increase economic efficiency, and ...
Klein, E., Mills, C.
core   +2 more sources

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