Results 51 to 60 of about 259,306 (230)

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Development of a theoretical framework based on the MAPR model for stage-based, individualized mobile smoking cessation interventions through systematic literature review and expert consultation

Zhongguo gonggong weisheng
ObjectiveTo develop a theoretical framework for stage-based, individualized mobile smoking cessation interventions to guide the design of smoking cessation applications (APPs).
Shuilian CHU, Hang JING, Lirong LIANG, Jun LI   +3 more
doaj   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Individualization and the Ideal of Self-Realization in Conditions of Reflexive Modernity

Communications, 2018
Individualization as a modernization social phenomenon is of a highly ambivalent character. On the one hand, it represents the emancipation of individuals from general pressures of the society, from the traditional relations of domination and material ...
Ciprian Turcan
doaj   +1 more source

Individualization of FSH Doses in Assisted Reproduction: Facts and Fiction

Frontiers in Endocrinology, 2019
The art of ovarian stimulation for IVF/ICSI treatment using exogenous FSH should be balanced against the relative contribution of other steps of the ART process such as the IVF-lab-phase and the Embryo-Transfer.
F. Broekmans
semanticscholar   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Individualized lightweight structures for biomedical applications using additive manufacturing and carbon fiber patched composites

Design Science, 2019
Combining additive manufacturing (AM) with carbon fiber reinforced polymer patched composites unlocks potentials in the design of individualized, lightweight biomedical structures.
Ralph Kussmaul, Manuel Biedermann, Georgios A. Pappas, Jónas Grétar Jónasson, Peter Winiger, Markus Zogg, Daniel-Alexander Türk, Mirko Meboldt, Paolo Ermanni   +8 more
doaj   +1 more source

The Vitrectomy Timing Individualization System for Ocular Trauma (VTISOT)

Scientific Reports, 2019
Ocular trauma is a major cause of monocular blindness worldwide. Vitrectomy at correct timing can significantly improve the efficacy and prognosis, but the timing of vitrectomy has remained highly controversial for decades.
Longhui Han, Jinchen Jia, Yiming Fan, Luyong Yang, Zhiqiang Yue, Wei Zhang, Fang Liu, Huan-jun Kang, Tao Huo, Shaolei Han, Hua Shen, Genquan Tian, Xu Su   +12 more
semanticscholar   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Radiotherapy for esophageal carcinoma: dose, response and survival

Cancer Management and Research, 2017
Yijun Luo,1,* Qingfeng Mao,2,3,* Xiaoli Wang,1 Jinming Yu,3 Minghuan Li3 1Department of Oncology, The People’s Hospital of Jiangxi, Nanchang, 2School of Medical and Life Sciences, University of Jinan-Shandong Academy of Medical Sciences ...
Luo Y, Mao Q, Wang X, Yu J, Li M
doaj