Results 91 to 100 of about 62,691 (272)

The influence of liver dysfunction on cyclosporine pharmacokinetics -A comparison between 70 per cent hepatectomy and complete bile duct ligation in dogs- [PDF]

, 1989
The influence of experimentally induced hepatic dysfunction on the pharmacokinetics of Cyclosporine A (CsA) was determined in dogs. The pharmacokinetics of oral (PO) and intravenous (IV) CsA were studied before and after 70 per cent hepatectomy or ...
B Sigel, BD Kahan, F Barbier, F Follath, G Burckart, G Paumgartner, GC Yee, GR Cherrick, Hisaaki Koie, I Sendama, Iman Zaghloul, JB Price, JM Hows, LF Rikkers, M Teranaka, R Mizumoto, R Venkataramanan, Raman Venkataramanan, RG Buice, RJ Sawchuk, Shunichi Takaya, Shunzaburo Iwatsuki, Takashi Noguchi, TE Starzl, Thomas E. Starzl   +24 more
core   +1 more source

Pharmacokinetics, safety, tolerability and fluorescence imaging of nizaracianine triflutate administered in three divided doses to healthy volunteers

British Journal of Clinical Pharmacology, EarlyView.
Aim Fluorescence‐guided surgery enhances intraoperative visualization of anatomical structures. Nizaracianine is a near‐infrared fluorescent agent that is exclusively renally cleared in animal models. It enables real‐time ureteral imaging and identification, potentially reduces risk of injury and facilitates assessment before surgical closure.
Lisanne K. A. Neijenhuis, Cedric M. W. Pesch, John V. Frangioni, Alexander L. Vahrmeijer, Jacobus Burggraaf, Naomi B. Klarenbeek   +5 more
wiley   +1 more source

Advancing design strategies in smart stimulus‐responsive liposomes for drug release and nanomedicine

BMEMat, EarlyView.
Schematic illustration of stimulus‐responsive liposomes designed for controlled drug release and nanomedicine. The innermost circle represents different liposomal structures, including unilamellar, multilamellar, and multivesicular liposomes. The middle layer illustrates the responsive phospholipid components.
Yuchen Guo, Nan Li, Daiwei Zhang, Jingya Gu, Zhihuan Liao, Zihao Teng, Xiangfu Du, Peter S. Timashev, Shipeng Chen, Shuaidong Huo   +9 more
wiley   +1 more source

Utility of intraoperative video-indocyanine green angiography in cerebral aneurysm clipping: a prospective observational study

Egyptian Journal of Neurosurgery
Background Surgical clipping of cerebral aneurysms aims to achieve complete aneurysm occlusion while preserving the patency of parent, branching, and perforating vessels.
Vemula Venkata Ramesh Chandra, Sree Datta Pradeep Kundum, Venkatesh Vinod Kharalkar, Praveen Yangannagari, Bodapati Chandra Mowliswara Prasad, Prithvi Kanduri   +5 more
doaj   +1 more source

Novel rodent models for macular research [PDF]

, 2010
Background: Many disabling human retinal disorders involve the central retina, particularly the macula. However, the commonly used rodent models in research, mouse and rat, do not possess a macula.
Huber, Gesine, Heynen, Severin, Imsand, Coni, vom Hagen, Franziska, Muehlfriedel, Regine, Tanimoto, Naoyuki, Feng, Yuxi, Hammes, Hans-Peter, Grimm, Christian, Peichl, Leo, Seeliger, Mathias W., Beck, Susanne Christiane   +11 more
core   +1 more source

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma, Songyan Li, Jie Yan, Xuechun Wang, Wen Zhao, Yunxuan Song, Dongdong Liu, Jianwei Jiao, Xiuying Duan, Guiqiang Zhang   +9 more
wiley   +1 more source

Visualization of Skin Perfusion by Indocyanine Green Fluorescence Angiography—A Feasibility Study

Plastic and Reconstructive Surgery, Global Open, 2017
Summary:. Plastic and reconstructive surgery relies on the knowledge of angiosomes in the raising of microsurgical flaps. Growing interest in muscle-sparing perforator flaps calls for reliable methods to assess the clinical feasibility of new donor sites
Johannes Steinbacher, MD, Hidehiko Yoshimatsu, MD, Stefan Meng, MD, Ulrike M. Hamscha, MD, Chun-Sheng Chan, MD, Wolfgang J. Weninger, MD, Chieh-Tsai Wu, MD, Ming-Huei Cheng, MD, MBA, FACS, Chieh-Han John Tzou, MD   +8 more
doaj   +1 more source

Reappraisal of birdshot retinochoroiditis (BRC): a global approach [PDF]

, 2018
Background: This study aimed to readjust the appraisal of birdshot retinochoroiditis (BRC) in light of a global approach, including the full array of investigational procedures.
Herbort, Carl, Papadia, Marina
core  

Pontos hipofluorescentes remotos em toxoplasmose ocular recorrente na angiografia com indocianina verde [PDF]

, 2007
PURPOSE: To report the findings of indocyanine green angiography performed in patients with recurrent ocular toxoplasmosis. METHODS: Institutional prospective analysis of 23 eyes from 23 immunocompetent patients with recurrent ocular toxoplasmosis aged ...
Abreu, Mariza Toledo, Amaro, Miguel Hage, Belfort, Rubens Junior, Muccioli, Cristina   +3 more
core   +3 more sources

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source