Results 111 to 120 of about 80,002 (339)

Marine Anoxia and Ocean Acidification During the End‐Permian Extinction

open access: yesGeophysical Monograph Series, Page 325-340., 2021

Exploring the links between Large Igneous Provinces and dramatic environmental impact

An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Ying Cui   +4 more
wiley  

+1 more source

Lithospermic Acid Improves Doxorubicin‐Induced Cardiomyopathy Through Sirtuin‐3‐Mediated Deacetylation of p53

open access: yesPhytotherapy Research, EarlyView.
Lithospermic acid (LA) inactivates the p53 signaling pathway via directly targeting SIRT3, thereby alleviating oxidative stress and abnormal apoptosis in the progression of doxorubicin (Dox)‐induced cardiomyocytes. ABSTRACT Doxorubicin (Dox)‐induced cardiomyopathy (DIC) is characterized by significant myocardial damage that can progress to dilated ...
Yining Zhao   +13 more
wiley   +1 more source

Temperature of cutaneous and subcutaneous tissue during the application of aerosols in rats

open access: yesActa Scientiarum. Health Sciences, 2014
This study compared the thermal changes of cutaneous and subcutaneous tissues exposed to different aerosols. Thirty-six adults Wistar rats were arranged in two treatment groups, one exposed to methyl salicylate (GSM; n = 9 skin and n = 9 subcutaneous ...
Andre de Oliveira Teixeira   +5 more
doaj   +1 more source

Constraints and Frugal Innovation: Enabling Sustainable Production Through the New Product Development Process

open access: yesSustainable Development, EarlyView.
ABSTRACT This paper advances understanding of how constraint‐based thinking fosters sustainable innovation under resource limitations. Based on five case studies of small and medium‐sized enterprises and research groups developing frugal medical devices across diverse regions, it identifies how market, infrastructure, and user constraints shape design ...
Zulfiya Ukbaeva   +2 more
wiley   +1 more source

Effect of General Hypothermia on the Embolic Model of Stroke in the Male Rat

open access: yesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2014
Introduction: Hypothermia has neuroprotective effects in permanent or transient models of cerebral artery occlusion. In the current study, neuroprotective effect of general hypothermia in the embolic model of stroke, in which no study has been conducted
V Ehsani   +7 more
doaj  

Current trends in neurocritical care: a comprehensive review [PDF]

open access: yesJournal of Neurocritical Care
Neurocritical care has evolved significantly by integrating technological advances, therapeutic innovations, and multidisciplinary approaches to enhance outcomes in patients with severe neurological conditions. Continuous neuromonitoring using tools like
Vinothini Murugaiyan   +2 more
doaj   +1 more source

Factors associated with post-arrest withdrawal of life-sustaining therapy. [PDF]

open access: yes, 2017
INTRODUCTION: Most successfully resuscitated cardiac arrest patients do not survive to hospital discharge. Many have withdrawal of life sustaining therapy (WLST) as a result of the perception of poor neurologic prognosis.
Abella, Benjamin S.   +7 more
core   +1 more source

Impact of general anaesthesia on immune response to first rabies vaccination in seronegative domestic cats

open access: yesVeterinary Record, EarlyView.
Abstract Background Despite common concerns, evidence that anaesthesia impairs vaccine efficacy remains limited. This study assessed the impact of general anaesthesia on the immune response to rabies vaccination in cats. Methods Thirty‐five healthy female cats (6–12 months old) undergoing elective spaying were enrolled.
Pierre Bessière   +8 more
wiley   +1 more source

AAKD: A standardized and comprehensive acupuncture anesthesia knowledge platform for enhanced recovery after surgery and mechanism

open access: yesVIEW, EarlyView.
Acupuncture anesthesia (AA) is an application of acupuncture innovation in surgical operations, combined with anesthetic techniques, and is a model of integrated Chinese and Western medicine. We proposed the Acupuncture Anesthesia Knowledge Database (AAKD), in which all data have been meticulously curated by field experts and assessed by a multi ...
Ying Wang   +11 more
wiley   +1 more source

The circadian system alters thermoregulation depending on the time of day and feeding condition [PDF]

open access: yes, 2009
The circadian rhythm of body temperature (Tb) is a well-known phenomenon. However, it is unknown how the circadian system affects thermoregulation. Food deprivation in mice induces a greater reduction of Tb particularly in the light phase.
Kei Nagashima, Ken Tokizawa, Yuki Uchida
core   +1 more source

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