Results 191 to 200 of about 11,557,218 (304)

Computational studies of peptide-induced membrane pore formation

Philosophical Transactions of the Royal Society B: Biological Sciences, 2017
R. Lipkin, T. Lazaridis
semanticscholar   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Obstetrical forceps induced Descemet’s membrane detachment (DMD)

JFO Open Ophthalmology
V. Jyothi Kiran, Balamurugan Ramatchandirane   +1 more
doaj   +1 more source

Clinical Outcomes of the Induced Membrane Technique for Infected Non-unions and Post-traumatic Bone Defects in a Resource-Limited Setting. [PDF]

Cureus
Dabhi S, Dhandhiya Y, Patel G.
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Proximity-induced membrane protein degradation for cancer therapies. [PDF]

RSC Med Chem
Zhang D, Wang Z, Inuzuka H, Wei W.
europepmc   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Osteotropic properties of mesenchymal stromal cells generated in Masquelet's induced membrane technique. [PDF]

Sci Rep
Suzuki M, Kamitakahara M, Kihara W, Xie C, Kato H, Fukawa Y, Hamagaki M, Aoki K, Ichihara S, Ishijima M, Ikeda T, Okuda T.   +11 more
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Effectiveness of the induced membrane technique in aseptic and infected long-bone defect management: Are there any differences? [PDF]

World J Orthop
Shastov AL, Kolchin SN, Malkova TA.
europepmc   +1 more source