Results 121 to 130 of about 4,733,094 (302)

Análisis genético y molecular del síndrome de Maroteaux-Lamy [PDF]

, 2008
[spa] Esta tesis es una contribución al conocimiento del síndrome de Maroteux-Lamy en el terreno de la genética molecular. El síndrome de Maroteaux-Lamy o mucopolisacaridosis de tipo VI (MPS VI) es una grave enfermedad hereditaria muy poco frecuente en ...
Garrido Fernández, Elena
core   +2 more sources

Kras and ciliary gene mutations cooperatively lead to pancreatic tumorigenesis only when induced during embryogenesis

Scientific Reports
Mutations in the Kras oncogene are present in approximately 25% of tumors, while defective primary cilium can either promote or suppress specific cancer types.
Angeline Fages, Memoona Rajput, Christine Sempoux, Patrick Jacquemin   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The role of APOBEC3-induced mutations in the differential evolution of monkeypox virus. [PDF]

Virus Evol, 2023
Li X, Habibipour S, Chou T, Yang OO.
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Mutations Induced by Carcinogens [PDF]

British Journal of Cancer, 1948
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Cover letter from the Kansas Induced Seismicity State Task Force to Governor Sam Brownback regarding the release of the State Action Plan for Induced Seismicity [2014]

, 2014
September 25, 2014 From: Rex Buchanan, Interim Director, Kansas Geological Survey; Mike Tate, Chief, Bureau of Water, Dept. of Health and Environment; Ryan Hoffman, Director, Conservation Division, Corporation Commission; State Task Force on Induced ...
Kansas Induced Seismicity State Task Force.
core  

Contribution of the SOS response and the DNA repair systems to norfloxacin induced mutations in E. coli. [PDF]

Mar Life Sci Technol, 2023
Lin T, Pan J, Gregory C, Wang Y, Tincher C, Rivera C, Lynch M, Long H, Zhang Y.   +8 more
europepmc   +1 more source