Results 171 to 180 of about 4,733,094 (302)

The complex role of genetic background in shaping the effects of spontaneous and induced mutations. [PDF]

Yeast, 2021
Goldstein I, Ehrenreich IM.
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

State Task Force on Induced Seismicity Releases Draft State Action Plan [2014]

, 2014
April 17 ...
Kansas Induced Seismicity State Task Force.
core  

Mismatch-Enhanced Specific PCR (MES-PCR): A Rapid and Cost-Effective Method for Screening CRISPR/Cas9-Induced Mutations. [PDF]

Biology (Basel)
Tian P, Yao B, Lin W, Yuan M, Li S, Qin Y, Chen S, Lai T, Yang Z, Lin W, Zhou X.   +10 more
europepmc   +1 more source

Inhibition of lateral shoot formation by RNA interference and chemically induced mutations to genes expressed in the axillary meristem of Nicotiana tabacum L. [PDF]

BMC Plant Biol, 2021
Hamano K, Sato S, Arai M, Negishi Y, Nakamura T, Komatsu T, Naragino T, Suzuki S.   +7 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

MUTACLASH: identifying functional small RNA target sites using crosslinking-induced mutations. [PDF]

RNA
Wu WS, Lee DE, Chung CJ, Lu SY, Brown JS, Zhang D, Lee HC.   +6 more
europepmc   +1 more source

Highly Efficient and Comprehensive Identification of Ethyl Methanesulfonate-Induced Mutations in Nicotiana tabacum L. by Whole-Genome and Whole-Exome Sequencing. [PDF]

Front Plant Sci, 2021
Udagawa H, Ichida H, Takeuchi T, Abe T, Takakura Y.   +4 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Discovery and Evaluation of Cadmium-Adapted Daphnia pulex Genotypes in a Region of Historical Mining Reveals Adaptation Protects the Germline From Cadmium-Induced Mutations. [PDF]

Mol Ecol
Keith N, Glaholt SP, Jackson CE, Young K, De Schamphelaere K, Colbourne JK, Shaw JR.   +6 more
europepmc   +1 more source