Results 31 to 40 of about 7,682,818 (299)

The role of the small intestine in the development of dietary fat-induced obesity and insulin resistance in C57BL/6J mice [PDF]

, 2008
Background Obesity and insulin resistance are two major risk factors underlying the metabolic syndrome. The development of these metabolic disorders is frequently studied, but mainly in liver, skeletal muscle, and adipose tissue.
Mechteld M Grootte Bromhaar, Jansen, Jenny, de Groot Philip J, Hooiveld Guido JEJ, Jansen Jenny, Vermeulen, J.J., Nicole JW de Wit, Jansen, J., Müller, M.R., Bosch-Vermeulen, Hanneke, van der Meer, Roelof, de Wit, Nicole J. W., Meer, R., van der, Bromhaar Mechteld, Wit, N.J.W., de, Philip J de Groot, Bosch-Vermeulen Hanneke, Hooiveld, Guido J. E. J., Müller Michael, Müller, Michael, Grootte Bromhaar, M.M., Michael Müller, de Groot, Philip J., Hanneke Bosch-Vermeulen, de Wit Nicole JW, Roelof van der Meer, Bromhaar, Mechteld M. Grootte, Jenny Jansen, Groot, P.J., de, Guido JEJ Hooiveld, Hooiveld, G.J.E.J., van der Meer Roelof, de Wit, Nicole JW, Mechteld Bromhaar   +33 more
core   +2 more sources

Impact of vanillin on postharvest disease control of apple

Frontiers in Microbiology, 2022
Apple fruits are susceptible to infection by postharvest fungal pathogens, which may cause fruit decay and severe economic losses. This study investigated the antifungal spectrum of vanillin against common decay pathogens of apple and explored the ...
Xiangyu Wang, Xuemin Zhang, Meng Sun, Li Wang, Yaoyuan Zou, Lin Fu, Chuanyu Han, Anqing Li, Limei Li, Chunyu Zhu   +9 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Azathioprine-Induced Warfarin Resistance [PDF]

Annals of Pharmacotherapy, 2008
To describe a case of azathioprine-induced warfarin resistance, present a literature review on warfarin-azathioprine interactions, and provide recommendations on appropriate management of this clinically significant interaction.A 29-year-old female with Cogan's syndrome experienced thrombosis of the left internal carotid artery. She was treated with an
Sara R, Vazquez, Matthew T, Rondina, Robert C, Pendleton   +2 more
openaire   +2 more sources

Induced terpene accumulation in Norway spruce inhibits bark beetle colonization in a dose-dependent manner [PDF]

, 2011
Background: Tree-killing bark beetles (Coleoptera, Scolytinae) are among the most economically and ecologically important forest pests in the northern hemisphere.
Anna-Karin Borg-Karlson, Hu, Jiang, Hu Jiang, Borg-Karlson, Anna-Karin,, Björklund, Niklas, Borg-Karlson Anna-Karin, Långström Bo, Christiansen Erik, Solheim, Halvor, Jiang Hu, Erik Christiansen, Solheim Halvor, Zhao, Tao,, Borg-Karlson, Anna-Karin, Krokene, Paal, Tao Zhao, Christiansen, Erik, Niklas Björklund, Hu, Jiang,, Paal Krokene, Krokene Paal, Zhao, Tao, Björklund Niklas, Halvor Solheim, Bo Långström, Zhao Tao, Långström, Bo, Björklund, Niklas,, Sveriges lantbruksuniversitet., Långström, Bo,, Christiansen, Eric,, Swedish University of Agricultural Sciences.   +31 more
core   +2 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Material Collected From the Induced Seismicity State Task Force Meeting, Wednesday, April 16, 2014, Newman University, Wichita, Kansas

, 2014
Announcement -- Agenda -- Breakout Sessions: Questions and Responses -- An Ounce of Understanding is Worth a Pound of Cure / by Kyle E. Murray -- Induced Seismicity and the Oil and Gas Industry -- Overview of Kansas Earthquakes / Rick Miller, Shelby ...
Induced Seismicity State Task Force Meeting (2014 : Wichita, Kan.)
core   +1 more source