Results 191 to 200 of about 1,306,598 (296)

Novel inducible nitric oxide synthase-inhibiting cytochalasins from an oyster-derived fungus Westerdykella dispersa Ca4-13: structural insights and molecular docking analysis. [PDF]

Bot Stud
Huang SJ, Hsu SJ, Wang SW, Liu YC, Jiang CY, Hsiao G, Lee TH.   +6 more
europepmc   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Microglia exhibit a dynamic response, modulating inducible nitric oxide synthase expression and the production of pro-inflammatory cytokines during experimental cerebral malaria. [PDF]

Front Immunol
Freire-Antunes L, Ornellas-Garcia U, Rangel-Ferreira M, Ribeiro-Almeida ML, Carvalho LJM, Daniel-Ribeiro CT, Ribeiro-Gomes FL.   +6 more
europepmc   +1 more source

The Role of High Cxcl11 Expression in Ovarian Dysfunction Through NF‐κB and AKT Pathways in a Thin Endometrium Mouse Model

iNew Medicine, EarlyView.
Thin endometrium upregulates Cxcl11, which polarizes ovarian macrophages via NF‐κB/AKT, impairing ovarian function. A new uter‐ovarian signaling axis is identified. ABSTRACT Objective Thin endometrium (TE) is a recognized cause of female infertility, primarily associated with impaired uterine receptivity.
Yulu Yang, Fei Tang, Zihan Meng, Yunxi Bao, Jujun Han, Xiaohua Jiang, Jianye Wang, Ying Wang, Zhaolian Wei   +8 more
wiley   +1 more source

A Refined Carbohydrate-Rich Diet Reduces Vascular Reactivity Through Endothelial Oxidative Stress and Increased Nitric Oxide: The Involvement of Inducible Nitric Oxide Synthase. [PDF]

Nutrients
Neumann K, Mawandji NBS, Schereider IRG, de Oliveira EC, Vieira JM, Bolsoni-Lopes A, Graceli JB, Dantas JA, Cardoso LS, Vassallo DV, Nunes KZ.   +10 more
europepmc   +1 more source

Metrnl: A Novel Therapeutic Target in Atherosclerosis

iNew Medicine, EarlyView.
ABSTRACT Atherosclerosis is a chronic inflammatory vascular disease and the main pathological basis of cardiovascular and cerebrovascular events. Exploration of endogenous protective factors in the disease is beneficial for the establishment of new therapeutic strategies.
Pin Wang, Dao‐Xin Wang, Chao‐Yu Miao
wiley   +1 more source

Hydroxyurea inhibits proliferation and stimulates apoptosis through inducible nitric oxide synthase in erythroid cells. [PDF]

Biomed Pharmacother
Dragojević T, Živković E, Diklić M, Ajtić OM, Lazarević M, Subotički T, Đikić D, Santibanez JF, Milenković D, Marković JD, Noguchi CT, Schechter AN, Čokić VP, Vukotić M.   +13 more
europepmc   +1 more source

Bisphenol A and Its Analogs: Toxicity Analysis in Mouse and Rat Liver—A Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) and its analogs are widely recognized for their use in industry and plastic manufacturing. Consequently, humans and animals are continually exposed to various substances in their daily lives. This review evaluates the hepatic toxicity of BPA and its analogs in mice and rats, with particular emphasis on molecular mechanisms ...
Sevda Bagdatli, Muhammed Canik, Gizem Gencay, Nurbanu Zengin, Tarık Dinc, Nazan Deniz Yön   +5 more
wiley   +1 more source

Riboflavin kinase binds and activates inducible nitric oxide synthase to reprogram macrophage polarization. [PDF]

Redox Biol
Shan X, Ji Z, Wang B, Zhang Y, Dong H, Jing W, Zhou Y, Hu P, Cui Y, Li Z, Yu S, Zhou J, Wang T, Shen L, Liu Y, Yu Q.   +15 more
europepmc   +1 more source

Electronic Structures and Orbital Interactions of Iron Porphyrin Intermediates Throughout Electrochemical CO2 Reduction Reaction: A Computational Study

Journal of the Chinese Chemical Society, EarlyView.
Electronic structure and orbital interactions of intermediates throughout electrochemically catalyzed CO2‐to‐CO reduction reaction by iron porphyrin are carefully discussed by DFT calculations in this work. The results demonstrate distinct functions of Fe 3d orbitals and porphyrin π* orbitals for electron transfer process to CO2, and the electronic ...
Ching‐Chin Chen
wiley   +1 more source