Results 91 to 100 of about 15,712 (268)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Residual magnetism in power transformer cores can cause severe inrush currents, threatening grid safety. The accuracy of residual magnetism testers depends on reference values from calibration platforms, yet current calibration platforms suffer from ...
Yuwei Wang +9 more
doaj +1 more source
From Color Induction to Brightness Induction
Retinal induction was studied in the light-adapted human retina by the method of electrostimulation. 1. The properties of retinal induction are qualitatively the same as in the dark-adapted retina except that its dissipation is more rapid. 2. There is an optimal intensity of adapting light for production of retinal induction. 3.
openaire +3 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Research on the Characteristics and Optimization of Pulse Discharge Reluctance Launching Circuit
To improve the projectile exit velocity of a reluctance launcher, this paper conducts a detailed analysis of the reluctance launch circuit, focusing on the number of turns of the cylindrical multi-layer solenoid solenoid, the total current, the ...
Wenda Qi +3 more
doaj +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
An accurate mathematical model of radial suspension forces for a bearingless permanent magnet slice motor (BPMSM) is of great significance to levitate the rotor stably and to improve the control accuracy of radial suspension force. In this paper, after a
Huangqiu Zhu, Suming Zhu
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Mutual inductance calculation for rectangular and circular coils with parallel axes
Simple and practical methods have been provided for the mutual inductance between rectangular and circular coils with parallel axes. The 2D Integral solution is given for the coils without the axial overlap.
Dongze Yu +6 more
doaj +1 more source

