Results 121 to 130 of about 129,379 (309)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Scalable quantum computing with Josephson charge qubits
, 2003 A goal of quantum information technology is to control the quantum state of a system, including its preparation, manipulation, and measurement. However, scalability to many qubits and controlled connectivity between any selected qubits are two of the ...
D. Deutsch +4 more
core +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
In this paper I raise concerns that I have with what I take to be a lack of warrant for Hume’s assertion that there are only two types of reasoning – demonstrative and probable. (Hume’s fork) What I leave for others to decide is whether this lack of warrant therefore successfully undercuts Hume’s argument for the Problem of Induction.
openaire +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Research on the Characteristics and Optimization of Pulse Discharge Reluctance Launching Circuit
IEEE AccessTo improve the projectile exit velocity of a reluctance launcher, this paper conducts a detailed analysis of the reluctance launch circuit, focusing on the number of turns of the cylindrical multi-layer solenoid solenoid, the total current, the ...
Wenda Qi +3 more
doaj +1 more source
Proceedings of the 9th conference on Theoretical aspects of rationality and knowledge, 2003 The paper explains enumerative induction, the confirmation of a law by its positive instances, in ranking theoretic terms. It gives a ranking theoretic explication of a possible law or a nomological hypothesis. And it shows, finally, that such schemes of enumerative induction uniquely correspond to mixtures of such nomological hypotheses.
openaire +3 more sources
High Kinetic Inductance NbN Nanowire Superinductors
, 2018 We demonstrate that a high kinetic inductance disordered superconductor can realize a low microwave loss, non-dissipative circuit element with an impedance greater than the quantum resistance ($R_Q = h/4e^2 \simeq 6.5k\Omega$).
Burnett, Jonathan +2 more
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source