Results 121 to 130 of about 45,041 (307)
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Abstract Proof by induction is commonplace in modern mathematics and computational logic. This paper overviews and discusses our recent results in turning saturation-based first-order theorem proving into a powerful framework for automating inductive reasoning.
Laura Kovács +3 more
openaire +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
MATHEMATICAL SIMULATION OF TRANSITION IN OUTPUT CIRCUIT OF CONTROLLABLE ELECTROCHEMICAL RESISTANCE
The problem of getting the analytical de pendence of the output value of the controllable electrochemical resistance (CER) on the control current is considered and solved.
Yury Y. Gerasimenko +2 more
doaj
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Inductance modeling for onchip interconnects [PDF]
. As the operation frequency reaches gigahertz in deep-submicron designs, the effects of inductance on noise and delay can no longer be neglected.
Wen-Zen Shen +4 more
core
From Color Induction to Brightness Induction
Retinal induction was studied in the light-adapted human retina by the method of electrostimulation. 1. The properties of retinal induction are qualitatively the same as in the dark-adapted retina except that its dissipation is more rapid. 2. There is an optimal intensity of adapting light for production of retinal induction. 3.
openaire +3 more sources
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
The Effect of Transformer Magnetizing Inductance on a Forward Converter with Current Mode Control
[[abstract]]The small-signal model for a forward converter with current-mode control is derived which includes the magnetizing inductance of the main power transformer.
Chen, S. Y. ; Huang, K. ; Chen, Jin-Jia
core
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source

