Results 171 to 180 of about 4,122,199 (286)

Influence of the laser welding process on changes in the magnetic induction of the Religa Heart ROT pump [PDF]

, 2019
Sebastian Stano, R. Kustosz, Artur Kapis, Przemysław Kurtyka, Jerzy Zalewski, Magda Zarwańska   +5 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Figure S5 from PHGDH Induction by MAPK Is Essential for Melanoma Formation and Creates an Actionable Metabolic Vulnerability

Neel Jasani, Xiaonan Xu, Benjamin Posorske, Yumi Kim, Kaizhen Wang, Olga Vera, Kenneth Y. Tsai, Gina M. DeNicola, Florian A. Karreth   +8 more
openalex   +1 more source

Induction of Functional Specific Antibodies, IgG-Secreting Plasmablasts and Memory B Cells Following BCG Vaccination

, 2022
Julia Bitencourt, Marco Polo Peralta Álvarez, Morven Wilkie, Ashley Jacobs, Daniel Wright, Salem Salman Almujri, Shuailin Li, Stephanie A. Harris, Steven G. Smith, Sean C. Elias, Andrew White, Iman Satti, Sally Sharpe, Matthew K. O’Shea, Helen McShane, Rachel Tanner   +15 more
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Advances in doubled haploid technology for rice breeding: mechanisms, applications, and future perspectives. [PDF]

Front Plant Sci
Lin Y, Mao F, Huang Y, Huang D, Wang K, Yan S, Liu C.   +6 more
europepmc   +1 more source

Evaluation of Lactobacillus delbrueckii Supernatant Effects on Cell Cycle Regulation, Apoptosis Induction, and Gene Expression in HT-29 Colorectal Cancer Cells.

Mohammad Reza Majid Khoshkholgh Pahlaviani, Amir Emami, Seyed Mohammad Mehdi Mahmoodi, Abbas Ali Rezaeian   +3 more
openalex   +2 more sources

B7-H3-targeting Fc-optimized antibody for induction of NK cell reactivity against sarcoma

, 2022
Ilona Hagelstein, Monika Engel, Clemens Hinterleitner, Timo Manz, Melanie Märklin, Gundram Jung, Helmut R. Salih, Latifa Zekri   +7 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Snorkel breathing technique in anesthesia: A narrative review. [PDF]

J Anaesthesiol Clin Pharmacol
Vaithialingam B, Karnate R.
europepmc   +1 more source