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Organ Preservation-Induction Chemotherapy [PDF]
, 2006 Induction chemotherapy consisting of high dose cisplatin and infusional 5-FU (PF) followed by definitive radiation therapy for the past decade has been the organ-sparing alternative to surgery for patients with laryngeal and hypopharyngeal squamous cell carcinomas.
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Induction Chemotherapy: To Use or Not to Use? That Is the Question
Seminars in Radiation Oncology, 2009The intensification of radiation, induction chemotherapy, and concomitant chemoradiotherapy has been extensively investigated over the past 2 decades for the nonsurgical management of locally advanced, nonmetastatic squamous cell head and neck cancer (HNC).
Everett E. Vokes, David M. Brizel
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Intra-arterial induction chemotherapy
Oncology Reports, 1996When effective anti-cancer drugs first became available to clinicians they were commonly used by surgeons by intra-arterial infusion to treat difficult regional cancer problems. Because they were most often used to treat poorly vascularised recurrent cancers results were, in general, unsatisfactory.
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Induction chemotherapy is the best timekeeper in nasopharyngeal carcinoma
Cancer, 2020NPC‐0501 has shown that induction chemotherapy provides a survival benefit for patients with locoregionally advanced nasopharyngeal carcinoma and has added evidence to current knowledge. In the intensity‐modulated radiotherapy era, neoadjuvant chemotherapy should be considered at least for patients with high‐risk disease.
Cavalieri S., Licitra L.
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INDUCTION CHEMOTHERAPY IN HEAD AND NECK CANCER [PDF]
Hematology/Oncology Clinics of North America, 1999 Induction chemotherapy can produce response rates of 60% to 90%, which are complete in 20% to 50% of previously untreated patients with squamous cell head and neck cancer. It was hoped that this dramatic chemotherapy-induced tumor shrinkage would result in more successful locoregional treatment and prove useful in disease management.
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Induction Chemotherapy for Hepatocellular Carcinoma
2011Hepatocellular carcinoma (HCC) is known as a relatively chemoresistant tumor, and systemic cytotoxic chemotherapy has failed to show a substantial benefit for patients with HCC. Other systemic therapies including hormonal therapy and immunotherapy have also been disappointing.
Takumi Fukumoto, Yonson Ku
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Induction Chemotherapy for Cervical Cancer
2011The standard of care in advanced cervical cancer in all stages from and above IB2 with tumors larger than 4 cm in diameter to stage IVA with invasion of the bladder or/and rectum is radiochemotherapy. In this setting intracavitary brachytherapy is the most active component for local tumor eradication and favourable long-term results.
Karl Reinhard Aigner, Josef Jansa
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Induction Chemotherapy for Breast Cancer
2016Induction chemotherapy, also known as primary, preoperative or neoadjuvant chemotherapy, for breast cancer is indicated in locally advanced breast cancer (LABC) and patients with stage II–III disease in order to downstage the tumour burden and ensure appropriate breast conservation.
Maria Angeles Gil-Delgado +2 more
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Induction of diffuse necrotizing enterocolitis by anticancer chemotherapy [PDF]
Gastroenterologia Japonica, 1987 Fulminant, necrotizing colitis is a frequent, and generally fatal, complication of severe granulocytopenia, occurring during the treatment of hematological malignancies. In these cases, the patient complains of severe peritonitis, including nausea, vomiting, abdominal pain, diarrhea or melena, and a high temperature.
Michio Maeta +2 more
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Induction chemotherapy for T4 lung cancer
European Surgery, 1999Background: The prognosis of patients with T4 nonesmall cell lung cancer (NSCLC) involving the mediastinum is uniformly poor, and surgery alone does not represent a successfull solution.
Erino A. Rendina +4 more
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