Results 131 to 140 of about 39,285 (359)
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Calculation of sub-surface-initiated fatigue fractures in gears [PDF]
, 2019 Power-transmitting gears are typically heat-treated, most often case-hardened, to improve the fatigue strength and therefore to ensure higher fatigue life.
Müller, Daniel +2 more
core
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Engine cyclic durability by analysis and material testing [PDF]
The problem of calculating turbine engine component durability is addressed. Nonlinear, finite-element structural analyses, cyclic constitutive behavior models, and an advanced creep-fatigue life prediction method called strainrange partitioning were ...
Halford, G. R., Kaufman, A.
core +1 more source
Weak entropy solutions to a model in induction hardening, existence and weak-strong uniqueness [PDF]
, 2020 Dietmar Hömberg, Robert Lasarzik
openalex +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Experimental Research on the Contact Fatigue of Induction Hardening Gear
Jixie chuandong, 1996 The induction hardening gears contact fatigue limit stress of two kinds of material were attained, and its “P S N” curues were carried out.The damage modality to teeth surface were recorded with the reversion technique of AC paper layer, and the ...
刘更新, 朱惠良
doaj
Deformation mechanisms of NiAl cyclicly deformed near the brittle-to-ductile transition temperature [PDF]
The intermetallic compound NiAl is one of many advanced materials which is being scrutinized for possible use in high temperature, structural applications.
Antolovich, Stephen D. +1 more
core +1 more source
A Novel Investigation Into the Edge Effect Reduction of 4340 Steel Disc Through Induction Hardening Process Using Magnetic Flux Concentrators [PDF]
, 2021 Mahyar Parvinzadeh +4 more
openalex +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source