Results 81 to 90 of about 39,285 (359)

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra, Nicholas F. Evageliou, Vandana Batra, Kristen L. Dalton, Stephanie Ortel, Usman Ashraf, Tricia R. Bhatti, Lisa J. States, Lea F. Surrey, Theodore W. Laetsch   +9 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

THE MECHANISM OF HARDENING OF ALLOYED STEELS IN IMPULSE MAGNETIC FIELD

Литьë и металлургия, 2012
In this paper, a model describing the mechanism of hardening steels in a pulsed magnetic field is provided. The model is based on the consideration of induction currents in the grain bulk ferrite, on the surface of the workpiece near the inductor.
A. V. Alifanov, Zh. A. Popova, N. M. Tsionenko   +2 more
doaj   +1 more source

Surface Hardening by Induction

Transactions of The Electrochemical Society, 1941
High frequency induction heating is ideal for localized surface hardening of crankshafts and a wide variety of machine parts. There is practically no distortion nor scale formation. Time cycles of only a few seconds are maintained by automatic regulation. The usual and expensive pretreatment, such as copper plating and carburizing, is eliminated.
openaire   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Effect of Different Microstructures on Surface Residual Stress of Induction-Hardened Bearing Steel

Metals
JIS SUJ2 steel is most widely used in bearing steel. The advantages are good hardenability, excellent fatigue, wear resistance and comprehensive mechanical properties. The wear resistance and fatigue resistance of this steel are attracting more attention,
Shao-Quan Lu, Liu-Ho Chiu
doaj   +1 more source

Comparison between two ultrasonic methods in their ability to monitor the setting process of cement pastes [PDF]

, 2009
This paper presents the comparison between ultrasonic wave transmission (USWT) method and ultrasonic wave reflection (USWR) method in their ability to monitor the setting process of cement pastes.
Akkaya, Franci Kavčič, Goran Turk, Gregor Trtnik, Grosse, Hewlett, Kamada, Keating, Korhonen, Krauss, Marko Ivan Valič, Rapoport, Reinhardt, Robeyst, Sayers, Schindler, Stepišnik, Sun, Sun, Trtnik, Valič, Voigt, Voigt, Voigt   +23 more
core   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Investigating the Wear Behaviour of Induction Hardened 100Cr6 Steel

Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2018
100Cr6steel surface was induction hardened in order to be used in a bushingmanufacturing. After examininig themicrostructure and hardness variations of the hardened surfaces, ball-on disctype wear tests were carried out.
Gülcan Toktaş, Alaaddin Toktaş, Murat Can Duran   +2 more
doaj   +1 more source