Results 61 to 70 of about 183,611 (299)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Accelerated Steady-State Torque Computation for Induction Machines using Parallel-In-Time Algorithms
, 2019 This paper focuses on efficient steady-state computations of induction machines. In particular, the periodic Parareal algorithm with initial-value coarse problem (PP-IC) is considered for acceleration of classical time-stepping simulations via non ...
Bast, Denys +3 more
core +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Electrical engineering & Electromechanics, 2023 Introduction. In this paper, a new approach for estimating the speed of in-wheel electric vehicles with two independent rear drives is presented. Currently, the variable-speed induction motor replaces the DC motor drive in a wide range of applications ...
A. Khemis, T. Boutabba, S. Drid
doaj +1 more source
Techno-economic comparison of operational aspects for direct drive and gearbox-driven wind turbines [PDF]
, 2010 The majority of wind turbines currently in operation have the conventional Danish concept design-that is, the three-bladed rotor of such turbines is indirectly coupled with an electrical generator via a gearbox.
Ault, G.W., McMillan, David
core +1 more source
Manipulation, machine induction, and bypassing
Philosophical Studies, 2022 AbstractA common style of argument in the literature on free will and moral responsibility is the Manipulation Argument. These tend to begin with a case of an agent in a deterministic universe who is manipulated, say, via brain surgery, into performing some action. Intuitively, this agent is not responsible for that action.
openaire +2 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Algerian Journal of Signals and SystemsThis paper deals with the power control of the cascaded doubly-fed induction generator (CDFIG) for wind energy applications. using a fractional order proportional integral (FOPI) controller within a field oriented control (FOC) scheme.
Sihem Djebbri, Samir Ladaci
doaj +1 more source
Detection of inter-turn faults in multi-phase ferrite-PM assisted synchronous reluctance machine [PDF]
, 2019 Inter-turn winding faults in five-phase ferrite-permanent magnet-assisted synchronous reluctance motors (fPMa-SynRMs) can lead to catastrophic consequences if not detected in a timely manner, since they can quickly progress into more severe short-circuit
Candelo Zuluaga, Carlos Andres +3 more
core +2 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source