Results 281 to 290 of about 170,221 (359)

Vibration Analysis of Aviation Electric Propulsion Test Stand with Active Main Rotor. [PDF]

Sensors (Basel)
Kliza R, Wendeker M, Drozd P, Siadkowska K.   +3 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Sterile innate immune mechanisms in neurodegenerative diseases. [PDF]

J Biol Chem
Ealy A, Serapiglia AM, Panicker N.
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Vibration, current, torque, RPM dataset for multiple fault conditions in industrial-scale electric motors under randomized speed and load variations. [PDF]

Data Brief
Jung W, Kim J, Jang K, Yun SH, Lim D, Jin M, Park YH.   +6 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Design optimization and real-time implementation of an LSPMSM for efficiency enhancement. [PDF]

Sci Rep
Ocak C, Yenipınar B, Çelik E, Abdel-Salam M, Tejani GG, Mousavirad SJ.   +5 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

E-MASS: Electromagnetic Mechanism for Active Shifting of the Centre of Gravity in Quadrotors Under Drive Fault. [PDF]

Sensors (Basel)
Kondratiuk M, Ambroziak L, Majka A, Venkatesha Prasad RR.   +3 more
europepmc   +1 more source

Electrostatically actuated MEMS resonators for magnetic and electric field sensing: a review. [PDF]

Microsyst Nanoeng
Koh D, Jung Y, Kim J.
europepmc   +1 more source