Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Speed Estimation of Six-Phase Induction Motors, Using the Rotor Slot Harmonics. [PDF]
Laadjal K +4 more
europepmc +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Analysis of Flux Density Distribution Effects on Rotor Bar Models to Improve Energy Efficiency, Environmental Sustainability, and Economic Outcomes in Induction Motors [PDF]
Induction motors are highly favored in industrial applications for their ease of operation, compactness, lightweight, efficiency, low maintenance, and cost-effectiveness. They are widely used in conveyors, compressors, crushers, drills, fans, escalators,
YANAWATI YAHYA +5 more
doaj
Geometric Analysis of Signals for Inference of Multiple Faults in Induction Motors. [PDF]
Contreras-Hernandez JL +6 more
europepmc +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Infrared Thermography Smart Sensor for the Condition Monitoring of Gearbox and Bearings Faults in Induction Motors. [PDF]
Alvarado-Hernandez AI +5 more
europepmc +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Coupled Electromagnetic-Dynamic Modeling and Bearing Fault Characteristics of Induction Motors considering Unbalanced Magnetic Pull. [PDF]
Huang L, Shen G, Hu N, Chen L, Yang Y.
europepmc +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source

