Results 51 to 60 of about 61,524 (294)

Induction of pre-hospital emergency anaesthesia i-PHEA: a national survey of UK HEMS practice

open access: yesBMC Emergency Medicine, 2023
Background Pre-hospital emergency anaesthesia is a critical intervention undertaken by helicopter emergency medical teams. Previous studies informed current practice for induction regimes, using a standardized approach of fentanyl, ketamine and ...
Mark Hodkinson, Kurtis Poole
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

The effect on post-operative pain of intravenous clonidine given before induction of anaesthesia

open access: yesIndian Journal of Anaesthesia, 2012
Background: Treatment of acute post-thoracotomy pain is particularly important not only to keep the patient comfortable but also to minimize pulmonary complications.
A. Samantaray, M. Rao, A. Chandra
semanticscholar   +1 more source

Isoflurane in paediatric anaesthesia [PDF]

open access: yesAnaesthesia, 1985
Summary The characteristics of induction with and recovery from isoflurane anaesthesia were studied in 248 children. The mean time to loss of consciousness was 1.5 min (SD 0.5). Tracheal intubation, without interruption of spontaneous ventilation, was accomplished in a mean time of 4.2 min (SD 54 seconds).
W S, Wren   +5 more
openaire   +2 more sources

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

CLINICAL FINDINGS FOLLOWING XYLAZINE-KETAMINE-QUAIFENESIN ANAESTHESIA IN EQUNES [PDF]

open access: yesJournal of Veterinary and Animal Sciences, 2000
The induction of anaesthesia with zylazineketamine ombination was smooth and rapid. Maintenance with a mixture composed of xylazine, ketamine and guaifenesin produced good depth of anaesthesia with adequate muscle relaxaton.
Jaisimha Rangaraj   +3 more
doaj  

Clinical efficacy and cardiorespiratory effects of alfaxalone, or diazepam/fentanyl for induction of anaesthesia in dogs that are a poor anaesthetic risk.

open access: yesVeterinary Anaesthesia and Analgesia, 2011
OBJECTIVE To evaluate the clinical efficacy and cardiorespiratory effects of alfaxalone as an anaesthetic induction agent in dogs with moderate to severe systemic disease. STUDY DESIGN Randomized prospective clinical study.
E. Psatha   +4 more
semanticscholar   +1 more source

CHANGES IN INTRAGASTRIC PRESSURE ON INDUCTION OF ANAESTHESIA

open access: yesBritish Journal of Anaesthesia, 1984
Intragastric pressure was measured in 20 patients before, and immediately after, the induction of anaesthesia with thiopentone. Intragastric pressure decreased in patients whose weights were the same as or less than expected, and increased in five of seven patients whose weights were greater than expected (P = 0.0013).
G B, Drummond, G R, Park
openaire   +3 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

The effect of intravenous granisetron on prophylactic ephedrine for preventing hypotension after general anaesthesia induction in elderly patients: a randomized controlled trial

open access: yesScientific Reports, 2023
Serotonin 3 receptor antagonists, a commonly used drug for preventing postoperative nausea and vomiting, have recently been reported to decrease the incidence of hypotension and the need for vasoactive drugs after spinal anaesthesia in obstetric surgery.
Youfa Zhou   +6 more
doaj   +1 more source

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