Results 31 to 40 of about 635 (191)

A Catalytic Osmium Redox Couple Collapses Cancer Redox Balance

Advanced Science, EarlyView.
A stable Os(III)/Os(IV) redox couple is developed to disrupt the tumor cell redox balance by concurrently catalyzing ROS generation and GSH depletion. Osmium‐treated cells exhibit multiple cell death pathways, including apoptosis, ferroptosis, and immunogenic cell death.
Wan‐Qiong Huang, Tao Huang, Yiming Hao, Gui‐Feng Huang, Yi‐Lang Yan, Xin Fang, Ying Chen, Xiao‐Long Wei, Wai‐Lun Man, Wen‐Xiu Ni   +9 more
wiley   +1 more source

An Embodied Paper‐Based Microfluidic Al‐Air Battery for Enduring Untethered Insect‐Scale Robots

Advanced Science, EarlyView.
This work presents a centimeter‐scale microfluidic aluminum–air battery (MFAAB) with dual‐surface anode and F−‐mediated byproduct decomposition. The design enables a high capacity of 2697.05 mAh/g Al and delivers tens of milliwatts to power LEDs, motors, and a toy car.
Yun Yang, Tao Jiang, Zhongyue Lu, Dapeng Fan, Zucheng Yi, Zirong Luo   +5 more
wiley   +1 more source

Bandgap‐Engineered PtxTey:Ag2Te Composite Quantum Dots Enable Programmable NIR‐II Imaging and Photothermal‐Immune Synergistic Therapy

Advanced Science, EarlyView.
A bandgap‐engineered PtxTey:Ag2Te quantum dot platform enables tunable NIR‐IIb emission for deep‐tissue imaging and mild photothermal therapy. Conjugation with αPD‐L1 confers dual tumor targeting and real‐time monitoring of PD‐L1 dynamics. Mild photothermal modulation induces immune reprogramming, enhancing checkpoint blockade efficacy and achieving ...
Jing Liu, Rui Xu, Quan Wu, Tian‐Xin Xiao, Lai‐Xi Zhao, Lei Sun, Ya‐Wen Zheng, Liang Dong, Zhi‐Quan Tian, Haibo Wang   +9 more
wiley   +1 more source

MiR‐940 Suppresses Ferroptosis by Controlling Expression of Key Regulatory Genes

Advanced Science, EarlyView.
A CRISPR‐based screening identified miR‐940 as a critical suppressor of ferroptosis in cancer. By coordinating the downregulation of pro‐ferroptotic genes with the upregulation of GPX4, miR‐940 establishes a regulatory network that protects against ferroptosis and correlates with poor clinical outcomes in distinct cancer entities.
Andrea Kolak, Juliane Tschuck, Stefanie A. I. Weiß, Daniel Kaemena, Karolin Klimm, Ana Galhoz, Larissa Ringelstetter, Myles Fennell, Juliane Merl‐Pham, Anna Artati, Stefanie Strasser, Ralph Garippa, Michael Witting, Hans Zischka, Joel A. Schick, Stefanie M. Hauck, Michael P. Menden, Michelle Vincendeau, Brent R. Stockwell, Kamyar Hadian   +19 more
wiley   +1 more source

Improving Sensitivity of an Inductive Pulse Sensor for Detection of Metallic Wear Debris in Lubricants Using Parallel LC Resonance Method

, 2013
Detection of small metallic wear debris is critical to identify abnormal wear conditions for prognosis of pending machinery failure. In this paper we applied an inductance–capacitance (LC) resonance method to an inductive pulse debris sensor to increase ...
Zhe, Jiang, Zhao, Liang, Xiaoliang, Zhu, Du, li   +3 more
core   +1 more source

Towards Advanced Intelligent and Perceptive Soft Grippers

Advanced Intelligent Systems, EarlyView.
Implementing soft yet strong and intelligent soft grippers request innovative and creative solutions in designing soft bodies and seamlessly integrating actuated systems with hierarchical sensing. This review systematically analyses soft grippers with a deep understanding of core components, from fundamental design principles to actuation and sensing ...
Haneul Kim, Hayeon Shin, Seik Park, Changbeom Shim, Seonggun Joe   +4 more
wiley   +1 more source

Probe Improvement of Inductive Sensor for Online Health Monitoring of Mechanical Transmission Systems

, 2015
Metal debris in lubricating oil contains abundant information regarding the ageing and wear/damage of mechanical transmission systems. The health condition of the lubricated systems can be indicated by the concentration and size of the metal abrasive ...
Wang, Chao, Chen, Zhe; id_orcid, Liu, Xiao   +2 more
core   +1 more source

Cerebrospinal Fluid from Restless Legs Syndrome Patients Reduces Iron Uptake in Blood–Brain Barrier Endothelial Cells by Disrupting the Regulation of Transferrin Receptors

Annals of Neurology, EarlyView.
Model figure of BBBECs TfR1 regulation in control and RLS: Graphical representation of TfR1 regulation in ECs by IRPs and representing it can be dysregulated by miR‐124‐3p in ECs of RLS. FPN1, ferroportin; BBBEC, blood‐brain barrier endothelial cells; IRP, iron regulatory proytein1/2; TfR1, Transferrin receptor; IRE, Iron responsive elements; Tf ...
Kondaiah Palsa, Aurosman Pappus Sahu, David B. Rye, Lynn Marie Trotti, Irina A. Elcheva, Vladimir S. Spiegelman, James R. Connor   +6 more
wiley   +1 more source

Characterization of Bio‐Based Phenolic Plasticizer Extracted From Rambutan Fruit Shell Waste: A Sustainable Alternative to Synthetic Plasticizers for Green Polymer Applications

Journal of the American Oil Chemists' Society, EarlyView.
Comprehensive Characterization of Bio‐Based Phenolic Plasticizer Extracted From Rambutan Fruit Shell Waste. ABSTRACT The development of eco‐friendly plasticizer is driving the interest of many scientists due to its environmentally benign nature.
Divya Divakaran, Indran Suyambulingam, Sunesh Narayanaperumal, Nadir Ayrilmis, Murugesan Palaniappan, Sivasubramanian Palanisamy, P. Senthamaraikannan, Siva Avudaiappan   +7 more
wiley   +1 more source

Experimental study on inductive method for online material loss detection with high debris concentration

, 2019
Online Oil debris detection is a complex and systemic issue that multiple requirements should be met for a practical application. When severe wear or tear happens, more accurate detection is needed for higher debris concentration.
Zio, E., Wang, S., Shi, J., Zio E., Hong, W, Shi J., Li, T, Wang S. P., Li T. Y., Hong W., Zio, Enrico   +10 more
core   +1 more source