Results 181 to 190 of about 6,288,402 (249)

An Injectable Metal‐Drug Supramolecular Condensate Enables Radiosensitization and Systemic Antitumor Immunity for Post‐Surgical Osteosarcoma Therapy

open access: yesAdvanced Science, EarlyView.
This work designed an injectable metal‐drug supramolecular condensate formed from hafnium ions and alendronate (Hf‐ALN) and loaded with the COX‐2 inhibitor celecoxib (CXB) for synergistic radioimmunotherapy of postoperative osteosarcoma. Mechanistically, upon X‐ray irradiation, Hf enhances radiation energy deposition, ROS generation, and DNA damage ...
Tianhua Xiao   +12 more
wiley   +1 more source

Polymer-Based Flexible Wireless Sensors for Health Monitoring. [PDF]

open access: yesNanomicro Lett
Huang H   +7 more
europepmc   +1 more source

Nanocluster‐Assisted OH Ligand Modification Optimizes Activity and Stability of Fe‐N‐C Catalysts

open access: yesAdvanced Science, EarlyView.
A nanocluster‐assisted ligand engineering stabilizes OH‐modified FeN4 active sites through strong electronic coupling between isolated Fe atoms and adjacent nanoclusters. This synergy optimizes oxygen‐intermediate adsorption, lowers ORR energy barriers, and breaks the conventional activity–stability trade‐off, enabling high ORR activity, exceptional ...
Xue Zhao   +6 more
wiley   +1 more source

Dual‐Functional Terahertz Manipulation of EuBa2Cu3O7 Superconductors via Cooper Pair Dynamics

open access: yesAdvanced Science, EarlyView.
We use a spintronic‐metasurface THz emitter to realize chiral THz generation. Using polarization‐tunable THz pulses, we investigate equilibrium and photoinduced THz responses in a 43 nm thick EuBa2Cu3O7 (EBCO) thin film. The EBCO film achieves 46.81 dB EMI shielding and 113% photoinduced THz modulation with 19.0 ps recovery, enabled by Cooper‐pair ...
Zhangshun Li   +10 more
wiley   +1 more source

The power of theory in the life sciences. [PDF]

open access: yesElife
Fine JL   +4 more
europepmc   +1 more source

Tumor Mechanical Remodeling via Bidirectional Calcium Redistribution Enables Deep Photothermal‐Immunotherapy

open access: yesAdvanced Science, EarlyView.
A bidirectional calcium‑redistributing nanomodulator rewires intra‑extracellular calcium homeostasis to remodel tumor mechanical microenvironments. It softens tumor stroma to facilitate deep tissue penetration while stiffening tumor cells, evoking amplified immunogenic cell death and robust CTL infiltration, which achieves potent deep photothermal ...
Hongjuan Zhao   +9 more
wiley   +1 more source

Sequential Regulation of Neurovascular Bone Regeneration in Large Bone Defects Using Black Phosphorus‐Europium Nanosheet Integrated TPMS Biomimetic Scaffold with Photo‐Controlled Ion Release

open access: yesAdvanced Science, EarlyView.
TPBE scaffolds, in conjunction with mild photothermal effects, effectively activate the PI3K/Akt signaling cascade, thereby promoting early neuronal differentiation and neurite growth. Short‐term (12 W) in vivo implantation studies revealed no significant pathological damage to major organs, providing preliminary evidence of the material's excellent ...
Bingqian Wang   +8 more
wiley   +1 more source

Mapping Embryonic Mouse Lung Development Using Enhanced Spatial Transcriptomics

open access: yesAdvanced Science, EarlyView.
The mammalian lung contains ∼50 cell types arranged along the airway epithelium. Here, deterministic barcoding sequencing (DBiT‐seq) is optimized to nearly double transcript recovery, enabling highly sensitive spatial mapping of the embryonic mouse lung.
Pengfei Zhang   +5 more
wiley   +1 more source

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