Results 251 to 260 of about 93,680 (316)

Enhanced the Trans‐Cleavage Activity of CRISPR‐Cas12a Using Metal‐Organic Frameworks as Stimulants for Efficient Electrochemical Sensing of Circulating Tumor DNA

open access: yesAdvanced Science, EarlyView.
This work designs manganese metal‐organic frameworks (Mn‐MOFs) co‐assembled with Cas12a/crRNA, enabling rapid release of Mn2⁺ under mild conditions. The MOFs‐induced proximity effect sustains Mn2⁺‐Cas12a/crRNA interactions, enhancing the trans‐cleavage activity of complex available to develop an electrochemical biosensor based on Mn‐MOFs‐enhanced ...
Shuai Wu   +8 more
wiley   +1 more source

High Proton Conductivity in xCuO/(1‐x)CeO2 Electrolytes Induced by CuO Self‐Nucleation and Electron‐Ion Coupling

open access: yesAdvanced Science, EarlyView.
This study discovers electron‐ion (E‐I) coupling in xCuO/(1‐x)CeO2(CCO), (x = 0–0.4) membranes, achieving ionic conductivity >0.15 S cm−1, with activation energy 0.28 eV and generated peak power density 900 mW cm−2 at 550 °C. Interfacial charge distribution and build‐in electric field enhanced ion transport entirely advanced the LT‐SOFC technology for ...
Muhammad Shahid Sharif   +8 more
wiley   +1 more source

Rationale and design of Healthy Kids Beyond the Bell: a 2x2 full factorial study evaluating the impact of summer and after-school programming on children's body mass index and health behaviors. [PDF]

open access: yesTrials
Weaver RG   +13 more
europepmc   +1 more source

A Bias‐Tunable Multispectral Photodetector Based on a GaN/TexSe1‐x Homo‐Type Heterojunction with a Unidirectional Barrier

open access: yesAdvanced Science, EarlyView.
A bias‐tunable multispectral photodetector based on a TexSe1‐x/GaN homo‐type heterojunction with a unidirectional barrier is proposed. By modulating the bias polarity and magnitude, the device's spectral response range can be extended from UV to the SWIR region.
Weijie Liu   +14 more
wiley   +1 more source

A Real‐Time Cell Death Self‐Reporting Theranostic Agent for Dynamic Optimization of Photodynamic Therapy

open access: yesAdvanced Science, EarlyView.
A cell death self‐reporting photodynamic theranostic nanoagent (CDPN) is developed that integrates photodynamic therapy (PDT) with real‐time K⁺ imaging to provide timely feedback on treatment responses. This approach enables the optimization of the drug‐light interval (DLI), a critical factor in PDT, resulting in significantly enhanced antitumor ...
Wei Bian   +9 more
wiley   +1 more source

A Promising MM–Fe–Al–Ga–B Permanent Material with Substantially Boosted Magnetic Performance

open access: yesAdvanced Science, EarlyView.
A facile two‐step strategy, Al‐doping toward high‐(BH)max followed by Nd/Pr‐based grain boundary diffusion processing toward high‐Hcj, endows the microcrystalline MM–Fe–Al–Ga–B magnet with substantially boosted magnetic performance [(BH)max = 28.02 MGOe, Hcj = 10.14 kOe].
Wang Chen   +9 more
wiley   +1 more source

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