Results 271 to 280 of about 93,680 (316)

A Copper‐Based Photothermal‐Responsive Nanoplatform Reprograms Tumor Immunogenicity via Self‐Amplified Cuproptosis for Synergistic Cancer Therapy

open access: yesAdvanced Science, EarlyView.
This study introduces cuproptosis nanoplatform, a novel nanoplatform using Cu2−XS hollow nanospheres, elesclomol, and lauric acid (LA) for self‐amplified cuproptosis. NIR‐II laser activation melts LA, releasing copper ions and elesclomol to enhance copper delivery within tumor cells, reduce glutathione's inhibitory effect, and trigger immunogenic cell ...
Runzi Cheng   +10 more
wiley   +1 more source

IL‐33‐Induced TREM2+ Macrophages Promote Pathological New Bone Formation Through CREG1‐IGF2R Axis in Ankylosing Spondylitis

open access: yesAdvanced Science, EarlyView.
This study identifies TREM2+ macrophages as key contributors to pathological bone formation in ankylosing spondylitis (AS). These macrophages mediate pathological new bone formation via the CREG1‐IGF2R‐PI3K‐AKT pathway and are regulated by IL‐33 through STAT6 phosphorylation.
Wenjun Hao   +16 more
wiley   +1 more source

Lack of Follow-Up in a Food-Insecure Population. [PDF]

open access: yesAm J Lifestyle Med
Domangue EE   +3 more
europepmc   +1 more source

Unlocking Methane Generation via Photo‐Thermal‐Coupled CO2 Hydrogenation by Integrating FeNiCrMnCo Multicomponent Alloy with GaN Nanowires

open access: yesAdvanced Science, EarlyView.
A noble‐metal‐free FeNiCrMnCo multicomponent alloy (MCA) integrated with GaN nanowires achieves efficient photo‐thermal‐coupled CO₂ methanation, delivering a methane production rate of 199 mmol∙g−¹∙h−¹ with 93% selectivity. The system demonstrates exceptional stability and tunable catalytic properties, offering a sustainable pathway for solar‐driven ...
Muhammad Salman Nasir   +9 more
wiley   +1 more source

Ultra–Efficient and Selective Gold Separation via Second–Sphere Coordination of Aurous Dihalide Using a Nonporous Amorphous Superadsorbent

open access: yesAdvanced Science, EarlyView.
A covalent organic superphane cage serves as a nonporous amorphous superadsorbent for highly efficient and selective gold separation. This material uniquely captures linear aurous dihalide ions, achieving exceptional uptake capacity and selectivity, and proving effective even in seawater, offering a scalable, eco–friendly solution to gold scarcity ...
Wei Zhou   +6 more
wiley   +1 more source

Recycling Defunct Lithium‐Ion Battery Cathodes to Quaternary Layered Double Hydroxides for Efficient Oxygen Evolution Reaction

open access: yesAdvanced Science, EarlyView.
Li(Co0.8Ni0.1Mn0.1)O2 and LiFePO4 cathode materials are functional recycled by simple leaching and co‐precipitation methods to synthesize Quaternary iron‐nickel‐cobalt‐manganese hydrotalcites as oxygen‐evolution‐reaction catalysts. The highly disordered structure and strong electronic interactions between metal cations result in excellent catalytic ...
Ronghou Yao   +11 more
wiley   +1 more source

Machine Learning ADME Models in Practice: Four Guidelines from a Successful Lead Optimization Case Study. [PDF]

open access: yesACS Med Chem Lett
Rich AS   +11 more
europepmc   +1 more source

Defect‐Engineered Multi‐Intermetallic Heterostructures as Multisite Electrocatalysts for Efficient Water Splitting

open access: yesAdvanced Science, EarlyView.
A self‐supporting nanoporous multicomponent CoCuMoNi catalyst is synthesized. Through the synergistic effect of multiphase interfaces, built‐in electric fields, and defect engineering, the binding energy of key reaction intermediates in hydrogen evolution reaction (HER)/oxygen evolution reaction (OER) is modulated, achieving high activity and stability
Xiang‐Feng Wu   +8 more
wiley   +1 more source

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