Results 201 to 210 of about 48,082 (256)

Defect‐Engineered BiO2‐X Nanosheets Mediate Sono‐Thermomechanical ECM Remodeling for Hepatocellular Carcinoma Immunotherapy

open access: yesAdvanced Science, EarlyView.
Herein, an ultrasound‐responsive BiO2‐X/siFn1 nanoplatform is developed to overcome anti‐PD‐1 resistance in hepatocellular carcinoma. Upon ultrasound irradiation, the platform downregulates fibronectin expression, while its sonothermal effect softens the dense extracellular matrix and activates antitumor immunity in the tumor microenvironment, thereby ...
Huimin Tian   +10 more
wiley   +1 more source

A Microenvironment‐Adaptive Scaffold Rejuvenates Peripheral Nerve Regeneration During Aging Via Dual Modulation of Ferroptotic Stimuli in Schwann Cells

open access: yesAdvanced Science, EarlyView.
(i) Aging impairs peripheral nerve regeneration via its dual ferroptosis‐mediated pathologies in senescent schwann cells. (ii) The composite nerve conduit is a symbiosis niche integrating microenvironment‐responsive nanoparticles (Ga‐PTAs) and maxillofacial‐derived mesenchymal stem cells (Mmscs).
Ning Zhan   +12 more
wiley   +1 more source

Precise Control of Charge–Structure Coupling in Polyamide Membranes for Mono‐ and Divalent Ion Separation

open access: yesAdvanced Science, EarlyView.
A zwitterionic copolymer, Poly(2‐methacryloyloxyethyl phosphorylcholine‐co‐2‐aminoethyl methacrylate hydrochloride) (P(MPC‐co‐AEMA)) copolymers, with tunable MPC/AEMA ratios, is grafted onto the polyamide (PA) selective layer via secondary interfacial polymerization. Balancing reactive anchoring segments (AEMA) and zwitterionic segments (MPC) regulated
Shaofan Duan   +13 more
wiley   +1 more source

Disentangling Elemental Roles in an Amorphous Medium‐Entropy Electrocatalyst for Oxygen Evolution

open access: yesAdvanced Science, EarlyView.
An amorphous medium‐entropy FeCoNiMo‐a catalyst with a unique nanoring architecture is synthesized via a solvothermal method. The catalyst exhibits exceptional stability in anion exchange membrane water electrolysis, maintaining stable operation for over 600 h at 1 A cm−2.
Jinhu Wu   +14 more
wiley   +1 more source

Hyper‐Intense Tumor Peripheral Accumulation of Antibody‐Conjugated Iron Oxide Nanoparticles can Enable Breast Cancer Detection by Magnetic Particle Imaging

open access: yesAdvanced Science, EarlyView.
Tumor‐associated inflammation retains antibody‐targeted or non‐specific antibody conjugated nanoparticles within the tumor microenvironment. Magnetic Particle Imaging (MPI) enables non‐invasive detection and differentiation of tumors from other organs, owing to higher nanoparticle retention by inflammatory cells in the tumor periphery.
Preethi Korangath   +9 more
wiley   +1 more source

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