Results 61 to 70 of about 42,406 (299)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
An Analytical Comparison of Interleaved Boost Converters with Different Inductor Configurations
This study presents a comparative analysis of coupled and uncoupled inductors within an interleaved boost converter. The study includes the derivation of steady-state variables and magnetic equations for each inductor configuration.
Arda Akyildiz +3 more
core +1 more source
Electrical engineering & Electromechanics, 2015 In the idealization of the "limiting low" frequencies of acting fields the calculated dependences for the density of the induced currents and distributed force of the attractive in the induction system with attractive screen and the external additional ...
Yu.V. Batygin +2 more
doaj
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
机车电传动, 2020 In order to facilitate the relevant personnel in the rail transit industry correctly understand and implement IEC 60310:2016 Railway application—Traction transformer and inductor on board rolling stock, the standard was explained from the aspect of ...
Delong YANG
doaj
Advanced Engineering Research, 2017 Introduction. An advanced technique of the livestock waste disinfection is considered. The essence of the method is in the integral physicochemical action of the alternating magnetic field combined with a chemical agent.
Nikolay V. Limarenko, Victor P. Zharov
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Additive Manufacturing as an Insulator for Medium Voltage Power Electronics Applications
IEEE AccessThe use of additive manufacturing (AM), more especially 3D printing, to medium voltage power electronics is examined in this research. It focuses on how this technology may transform insulating techniques and component manufacture.
Faisal Alsaif
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source