Results 31 to 40 of about 298,020 (262)

Development of industrial areas on the territory of Moscow and their reorganization at the turn of the 21 st century

open access: yesPrace Komisji Geografii Przemysłu Polskiego Towarzystwa Geograficznego, 2010
The article outlines the main features of the development of industrial areas (zones) on the territory of Moscow and their reorganization in the period 1990-2009.
Sergey Elagin
doaj   +1 more source

Brownfield redevelopment as a measure for climate changes mitigation [PDF]

open access: yesZbornik Radova: Geografski institut "Jovan Cvijić", 2013
This paper explores brownfield renewal as a measure of sustainable land use. The aim was to highlight the brownfield redevelopment as a strategy for mitigation of negative effects of climate changes.
Cizler Jasna
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Norfloxacin degradation by Bacillus subtilis strains able to produce biosurfactants on a bioreactor scale

open access: yesE3S Web of Conferences, 2017
The discharge of antibiotics into the environment has become a major concern since this group of pharmaceuticals influence on microbial communities not only by its mode of action, but also because of the risk of a worldwide dispersal of antibiotic ...
Jałowiecki Łukasz   +2 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Effect of some Soil Properties on Heavy Metal Contents in Soil Qena Governorate. [PDF]

open access: yesJournal of Soil Sciences and Agricultural Engineering, 2017
This study aims to assess heavy metal in the soils of Qena governorate. To fulfill this objective, surface soil samples were collected from  industrial site  and agricultural soils in Qena governorate. Cd. Co, Cr, Cu, Fe, Mn, Ni, Pb and Zn in the samples
M. Nazir   +3 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

A PHREEQC-Based Tool for Planning and Control of In Situ Chemical Oxidation Treatment

open access: yesApplied Sciences
This article describes a tool that can be used to improve the effectiveness of the ISCO (in situ chemical oxidation) method. It is an Excel-based application that uses Visual Basic, PHREEQC, and Python.
Katarzyna Samborska-Goik   +3 more
doaj   +1 more source

City and Industry: How to Cross Borders? Learning From Innovative Company Site Transformations

open access: yesUrban Planning, 2021
While working and living coexisted in the historical city, the functions are separated in the Modernist city. Recently, the idea of connected urban districts with short distances and attractive work spaces have received renewed attention from companies ...
Britta Hüttenhain, Anna Ilonka Kübler
doaj   +1 more source

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