Results 51 to 60 of about 7,793,912 (309)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

On System Dynamics: An Evaluation on the Impact of Integrating Artificial Intelligence (AI) in a Solar-Powered Hydroponics System in a Local Philippine Community

Proceedings
This study explores the integration of Artificial Intelligence (AI) and solar-powered hydroponics to improve agricultural sustainability in Philippine barangays [...]
Jay Emanuel Quiroz Alegarbes, Amando Radomes   +1 more
doaj   +1 more source

BUSINESS MODEL CANVAS AS AN ANALYTICAL TOOL FOR THE EVALUATION OF COMPANIES: CASE STUDY FOR THE AUDIOVISUAL INDUSTRY IN BOGOTA, COLOMBIA

South African Journal of Industrial Engineering, 2019
The paper discusses analytical applications of the business model canvas (BMC) formulated by Osterwalder & Pigneur [1]. From this model, a methodological tool was devised and used as part of an academic research project, in which the categories (blocks ...
Ruiz-Ramirez, Jessica Alejandra , Reyes-Cancino, Diego Felipe , Arenas-Castro, Carlos Julio   +2 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

A gap study between industry expectations and current competencies of bachelor’s degree graduates in industrial engineering in Thailand 4.0 era: A case study of industrial engineering graduates of Khon Kaen University

Cogent Education, 2022
The purpose of this research is to study the gap between industry expectations and the current competencies of bachelor’s degree industrial engineering graduates in Khon Kaen University in Thailand 4.0 era so that the research results of this study may ...
Nattariga Chaengpromma, Sirorat Pattanapairoj   +1 more
doaj   +1 more source

An Industrial Engineering approach to power management logic [PDF]

, 2011
Thesis (B Eng.
Snyman, Matthys Gerhardus
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

A proposal of teaching operational research in online contexts: An experience with SageMath in Brazil

Engineering Reports
The paper analyzes how to improve the teaching of Operational Research, focusing on distance learning courses where professors and students are separated through space and time.
Georgia de Souza Assumpção, Carolina Maia dos Santos, Daniele de Lima Campello, Leonardo Silva deLima, Alexandre de Carvalho Castro   +4 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source