Results 41 to 50 of about 107,243 (264)

Foundation language models through the lens of manufacturing

open access: yesProduction and Manufacturing Research: An Open Access Journal
Although recent studies have focused on foundation language models’ architectures, scaling properties, and applications in fields such as healthcare and business, no detailed investigation has addressed their role in manufacturing.
Sareh Aghaei, Fazel Ansari
doaj   +1 more source

Model Predictive collision-free path following control for nonholonomic mobile robots [PDF]

open access: yesFME Transactions, 2023
In this research, a model predictive collision-free path following controller is developed and applied for an omnidirectional mobile robot (OMR). The mobile robot is controlled to track a reference path while avoiding collision with obstacles.
Hiep Thai Thanh   +2 more
doaj  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Energy Efficiency Improvement of Diesel–Electric Trains Using Solar Energy: A Feasibility Study

open access: yesApplied Sciences, 2022
Nowadays, productivity challenges in modern manufacturing systems have been the driving force in generating energy-efficient technologies in every industry, including diesel–electric locomotives.
Ahmad Fayad   +4 more
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

A task‐centric knowledge graph construction method based on multi‐modal representation learning for industrial maintenance automation

open access: yesEngineering Reports
Maintenance manuals are crucial information sources for maintenance and repair. Prior studies explored factual knowledge extraction from textual documents.
Zengkun Liu, Yuqian Lu
doaj   +1 more source

Sistema especialista de 2ª geração para diagnose técnica: modelo e procedimento 2nd generation expert system for technical diagnosis: a model and a procedure

open access: yesGestão & Produção, 1994
Este trabalho trata da diagnose em equipamentos industriais através do uso de Sistemas Especialistas. Com o objetivo de desenvolver procedimentos que contribuam na construção de Sistemas Especialistas para diagnose em Manutenção Industrial, consideramos ...
Néocles Alves Pereira
doaj   +1 more source

Energy Recovering Using Regenerative Braking in Diesel–Electric Passenger Trains: Economical and Technical Analysis of Fuel Savings and GHG Emission Reductions

open access: yesEnergies, 2021
Rail transport, specifically diesel–electric trains, faces fundamental challenges in reducing fuel consumption to improve financial performance and reduce GHG emissions.
Ahmad Fayad   +4 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

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