Results 41 to 50 of about 1,141,941 (333)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Health Maintenance in Industry
American Journal of Public Health and the Nations Health, 1938 Health Maintenance in Industry-By J. D. Hackett. Chicago & New York: A. W. Shaw Co., 1925. xx+488 pp. Price, $5.00. This book, by a lecturer in New York University, on labor and employment management is a masterpiece with a strong appeal to industrial managers to grasp the economics of health maintenance in industry, and to industrial physicians to ...
openaire +3 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Model Predictive collision-free path following control for nonholonomic mobile robots [PDF]
FME Transactions, 2023 In this research, a model predictive collision-free path following controller is developed and applied for an omnidirectional mobile robot (OMR). The mobile robot is controlled to track a reference path while avoiding collision with obstacles.
Hiep Thai Thanh +2 more
doaj
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Foundation language models through the lens of manufacturing
Production and Manufacturing Research: An Open Access JournalAlthough recent studies have focused on foundation language models’ architectures, scaling properties, and applications in fields such as healthcare and business, no detailed investigation has addressed their role in manufacturing.
Sareh Aghaei, Fazel Ansari
doaj +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Energy Efficiency Improvement of Diesel–Electric Trains Using Solar Energy: A Feasibility Study
Applied Sciences, 2022 Nowadays, productivity challenges in modern manufacturing systems have been the driving force in generating energy-efficient technologies in every industry, including diesel–electric locomotives.
Ahmad Fayad +4 more
doaj +1 more source
Current Tracking Adaptive Control of Brushless DC Motors
International Journal of Adaptive Control and Signal Processing, EarlyView.In this paper, the current tracking for Brushless Direct Current motors is approached considering uncertainty in the parameters of the motor's model. An adaptive control scheme to compensate electrical parameters uncertainty is proposed without requiring any knowledge of the mechanical parameters.
Fernanda Ramos‐García +3 more
wiley +1 more source
Energies, 2021 Rail transport, specifically diesel–electric trains, faces fundamental challenges in reducing fuel consumption to improve financial performance and reduce GHG emissions.
Ahmad Fayad +4 more
doaj +1 more source