Results 271 to 280 of about 913,632 (347)

Dendrimer Conjugates with PD‐L1‐Binding Peptides Enhance In Vivo Antitumor Immune Response

Advanced Healthcare Materials, EarlyView.
In this paper, a novel nanoparticle scaffold composed of dendrimers conjugated with peptide‐based immune checkpoint inhibitors, enhancing drug delivery efficacy is introduced. By conjugating PD‐L1‐binding peptides to dendrimers, multivalent binding effects are harnessed, resulting in enhanced binding affinity, prolonged half‐life, and improved ...
DaWon Kim, Jin Woong Lee, Piper A. Rawding, Mari Iida, Carter Kim, Kourtney L. Kostecki, Michael J. Poellmann, Bridget Crossman, Ashley S. Liu, YoungSoo Kim, Deric L. Wheeler, Seungpyo Hong   +11 more
wiley   +1 more source

Author Correction: Artificial intelligence-enhanced diagnosis of degenerative joint disease using temporomandibular joint panoramic radiography and joint noise data. [PDF]

Sci Rep
Choi E, Shin S, Lee K, An T, Lee RK, Kim S, Son Y, Kim ST.   +7 more
europepmc   +1 more source

Combination of Polydopamine and Plasma Oxidation to Increase Tissue Integration of Polyurethane‐Silicone Copolymers for Cardiovascular Implants

Advanced Healthcare Materials, EarlyView.
Plasma oxidation following polydopamine deposition can significantly reduce the surface hydrophobicity of polyurethane‐siloxanes without impacting surface roughness, thereby increasing fibroblast viability, adhesion, and extracellular matrix production and secretion.
Sophie Armstrong, Jennifer M. Dyson, Lingxiao Zeng, Saeedreza Zeibi Shirejini, John S. Forsythe, Shaun D. Gregory   +5 more
wiley   +1 more source

Association of workplace infection control and perceived organizational support on worker loneliness during the COVID-19 pandemic. [PDF]

Front Public Health
Funada M, Noguchi S, Matsugaki R, Odagami K, Hino A, Tateishi S, Tsuji M, Yatera K, Matsuda S, Fujino Y.   +9 more
europepmc   +1 more source

Direct Surface Modification of the Epidermis Using Mussel‐Inspired Polydopamine with Multiple Anti‐Biofouling Functions

Advanced Healthcare Materials, EarlyView.
Surface modification using mussel‐derived polydopamine (PDA) is a versatile and robust biocompatible strategy that enables direct application to various epidermal surfaces, regardless of their morphological complexity or surface characteristics. The PDA‐coated epidermis exhibits multiple anti‐biofouling functionalities, including antibacterial and anti‐
Su Eon Lee, Hanna Lee, Jang Hwan Kim, Sungwook Park, Young Taek Oh, Hayoung Choi, Jeong‐Min Kim, Hye‐Jun Jo, Jun Hyun Park, Ho Jun Jin, Kwan Hyi Lee, Seung Ho Han, Hojun Kim, Jun Kyun Oh, Bong Hoon Kim   +14 more
wiley   +1 more source

Risk of Insulin Resistance: Comparison of the Commerce vs. Industry Sector and Associated Variables. [PDF]

Diseases
Pilar Fernández-Figares Vicioso M, Riutord Sbert P, López-González ÁA, Ramírez-Manent JI, Del Barrio Fernández JL, Herrero MTV.   +5 more
europepmc   +1 more source

Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo

Advanced Healthcare Materials, EarlyView.
This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla, Vincenzo Verdi, Willemijn de Voogt, Mariona Estapé Sentí, Arnold C. Koekman, Julian Rietveld, Sven van Kempen, Qiangbing Yang, Juliette van Merris, Guido Jenster, Martin E. van Royen, Marcel H. Fens, Sander A. A. Kooijmans, Wytske M. van Weerden, Guillaume van Niel, Pieter Vader, Raymond M. Schiffelers   +16 more
wiley   +1 more source

Cross-sectional associations between multiple plasma heavy metals and lung function among elderly Chinese. [PDF]

Sci Rep
Yu J, Zhang R, Yang A, Yang J, Zhang Y, Wu R, Luo F, Luo H, Chen R, Luo B, Ma L.   +10 more
europepmc   +1 more source

Decoding Hydrogel Porosity: Advancing the Structural Analysis of Hydrogels for Biomedical Applications

Advanced Healthcare Materials, EarlyView.
Porosity governs transport mechanics in hydrogels, yet characterization in its native state remains challenging. This work harnesses particle tracking to uncover three‐dimensional pore geometric features in polyethylene glycol hydrogels. Measurements in the native state reveal pores characteristics are comparable to those obtained by cryogenic scanning
M. A. Kristine Tolentino, Eric Y. Du, Giulia Silvani, Elvis Pandzic, Kristopher A. Kilian, J. Justin Gooding   +5 more
wiley   +1 more source

Biochemical characterization of lipase from Cryptococcus albidus (D24) and its application in sugar fatty acid ester synthesis. [PDF]

Arch Microbiol
Yilmaz DE, Kula C, Demirci H.
europepmc   +1 more source